Convules CR 300 mg (Tablet (Controlled Release))
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
Category | Details |
---|---|
Generic | Sodium valproate |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Treatment of all types of epilepsy
- Treatment of bipolar disorder
- Prophylaxis of migraine
- Prophylaxis of febrile convulsion
- Prophylaxis of post-traumatic epilepsy
Composition
- Sodium Valproate tablet contains 200 mg BP
- Sodium Valproate syrup contains 200 mg BP in 5 ml
- Sodium Valproate controlled release tablets in 200mg, 300mg, and 500mg
- Sodium Valproate injection contains Sodium Valproate BP eqv. to Valproic Acid 500 mg in 5 ml
Pharmacology
- Anti-epileptic activity against a variety of seizures
- Increase in brain levels of gamma-aminobutyric acid (GABA)
Dosage & Administration
- Oral and injection administration
- Initial and maintenance dosage for adults and children
- Dosage adjustments for different conditions
- Intravenous infusion for adults and children
Interaction
- Non specific inhibitor of drug metabolism
- Interacts significantly with Phenobarbital, Phenytoin, Warfarin, Aspirin
Contraindications
- Known hypersensitivity to the drug
- Liver dysfunction
- Restricted use during pregnancy and in women of childbearing potential
Side Effects
- Anorexia, nausea, vomiting
- CNS effects including sedation, ataxia, tremor
- Rash, alopecia, stimulation of appetite
- Elevation of liver enzymes in plasma
- Fulminate hepatitis
- Acute pancreatitis
- Hyperammonemia
Pregnancy & Lactation
- Causes neural tube defects in newborn if exposed in the first trimester
- Excretion in breast milk
- No risk to the child through breast-feeding
Precautions & Warnings
- Monitoring of liver functions
- No undue potential for bleeding before surgery
- Care in renal impairment, pregnancy, breast-feeding, systemic lupus erythematosus
- False interpretation of urine ketone test
- Avoid sudden withdrawal of therapy
Therapeutic Class
- Primary anti-epileptic drugs
Storage Conditions
- Do not store above 30°C
- Keep away from light and out of the reach of children
Related Brands
- Convules CR 200 mg (Tablet (Controlled Release)) - opsonin-pharma-ltd
- Valepi 200 mg (Tablet) - medimet-pharmaceuticals-ltd
- Proval CR 500 mg (Tablet (Controlled Release)) - general-pharmaceuticals-ltd
- Proval CR 300 mg (Tablet (Controlled Release)) - general-pharmaceuticals-ltd
- Nalipsy 200 mg (Tablet) - drug-international-ltd