Adlock 40 mg (Tablet)

Indications

• Essential hypertension
• Angina pectoris
• Cardiac arrhythmia
• Thyrotoxicosis
• Anxiety
• Prophylaxis of migraine

Pharmacology

Blocks B-adrenergic receptors, used in hypertension and angina pectoris, absorbed from gastrointestinal tract, metabolized by the liver, excreted through the urine

Dosage & Administration

• Adult:
  • Hypertension:
    • Initially 80 mg twice daily
    • Maintenance dose of 160-320 mg daily
  • Angina pectoris:
    • Initially 40 mg 2-3 times daily
    • Maintenance dose of 120-240 mg daily
  • Thyrotoxicosis: 10-40 mg, 3-4 times daily
  • Anxiety:
    • 40 mg once daily
    • May be increased to three times daily
  • Prophylaxis of migraine:
    • Initially 40 mg 2-3 times daily
    • Maintenance dose of 80-160 mg daily
• Child:
  • Hypertension:
    • Neonate: 0.25-0.5 mg/kg 3 times daily
    • Child 1 month-12 years: 0.25-1 mg/kg 3 times daily
    • Child 12-18 years: Initially 80 mg twice daily, maintain 160-320 mg daily

Interaction

Patients receiving verapamil, salbutamol, Levosalbutamol, ergot alkaloids, lidocain, phenobarbital drugs should be closely observed during therapy

Contraindications

• Bronchospasm
• Cardiogenic shock
• Second or third degree heart block
• Diabetes mellitus

Side Effects

• Cold extremities
• Lassitude
• Nausea
• Dizziness
• Insomnia
• Paresthesia

Pregnancy & Lactation

Pregnancy category C, should not be used in pregnant women. Propranolol is excreted in human milk. Caution should be taken when propranolol is administered to a nursing mother

Precautions & Warnings

Should be taken with caution in hepatic and renal impairment, pregnancy and lactating mother

Therapeutic Class

• Beta-adrenoceptor blocking drugs
• Beta-blockers

Storage Conditions

Store in a cool and dry place, protected from light

Related Brands

• Adlock 10 mg (Tablet) - sonear-laboratories-ltd