Eval 250 mg (Tablet)
Unit Price: ৳ 3.50 (3 x 10: ৳ 105.00)
Strip Price: ৳ 35.00
Medicine Details
Category | Details |
---|---|
Generic | Sodium valproate |
Company | Unimed unihealth pharmaceuticals ltd |
Also available as |
Indications
- Treatment of all types of epilepsy
- Treatment of bipolar disorder
- Prophylaxis of migraine
Composition
- Sodium Valproate tablet 200mg
- Sodium Valproate syrup 200mg/5ml
- Sodium Valproate controlled release 200 tablet
- Sodium Valproate controlled release 300 tablet
- Sodium Valproate controlled release 500 tablet
- Sodium Valproate injection 500mg/5ml
Pharmacology
- Anti-epileptic activity
- Increase brain levels of gamma-aminobutyric acid (GABA)
Dosage & administration
- Range of dosage for adults for epilepsy
- Range of dosage for children for epilepsy
- Dosage for bipolar disorder
- Dosage for prophylaxis of migraine
- Dosage for injection in adults
- Dosage for injection in children
Interaction
- Non-specific inhibitor of drug metabolism
- Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin
Contraindications
- Hypersensitivity to the drug
- Liver dysfunction
- Restricted use during pregnancy and in women of childbearing potential
Side effects
- Common side effects: anorexia, nausea, vomiting
- CNS effects: sedation, ataxia, tremor
- Other effects: rash, alopecia, stimulation of appetite
- Hepatic function effects: elevation of liver enzymes, fulminate hepatitis
- Prone to suffer from hepatic injury, acute pancreatitis, hyperammonemia
Pregnancy & lactation
- Crosses the placenta
- Associated with neural tube defects in newborns
- Excreted in breast milk
- No risk to the child from breast-feeding mothers
Precautions & warnings
- Monitoring of liver functions
- Check for potential bleeding before surgery
- Care in renal impairment, pregnancy, breast-feeding, and systemic lupus erythematosus
- Partially eliminated in the urine as a ketone metabolite
- Avoid sudden withdrawal of therapy
Therapeutic class
- Primary anti-epileptic drugs
Storage conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children