Eval 250 mg (Tablet)

Unit Price: ৳ 3.50 (3 x 10: ৳ 105.00)
Strip Price: ৳ 35.00

Medicine Details

Indications

  • Treatment of all types of epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine

Composition

  • Sodium Valproate tablet 200mg
  • Sodium Valproate syrup 200mg/5ml
  • Sodium Valproate controlled release 200 tablet
  • Sodium Valproate controlled release 300 tablet
  • Sodium Valproate controlled release 500 tablet
  • Sodium Valproate injection 500mg/5ml

Pharmacology

  • Anti-epileptic activity
  • Increase brain levels of gamma-aminobutyric acid (GABA)

Dosage & administration

  • Range of dosage for adults for epilepsy
  • Range of dosage for children for epilepsy
  • Dosage for bipolar disorder
  • Dosage for prophylaxis of migraine
  • Dosage for injection in adults
  • Dosage for injection in children

Interaction

  • Non-specific inhibitor of drug metabolism
  • Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin

Contraindications

  • Hypersensitivity to the drug
  • Liver dysfunction
  • Restricted use during pregnancy and in women of childbearing potential

Side effects

  • Common side effects: anorexia, nausea, vomiting
  • CNS effects: sedation, ataxia, tremor
  • Other effects: rash, alopecia, stimulation of appetite
  • Hepatic function effects: elevation of liver enzymes, fulminate hepatitis
  • Prone to suffer from hepatic injury, acute pancreatitis, hyperammonemia

Pregnancy & lactation

  • Crosses the placenta
  • Associated with neural tube defects in newborns
  • Excreted in breast milk
  • No risk to the child from breast-feeding mothers

Precautions & warnings

  • Monitoring of liver functions
  • Check for potential bleeding before surgery
  • Care in renal impairment, pregnancy, breast-feeding, and systemic lupus erythematosus
  • Partially eliminated in the urine as a ketone metabolite
  • Avoid sudden withdrawal of therapy

Therapeutic class

  • Primary anti-epileptic drugs

Storage conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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