Eval 250 mg (Tablet)

Unit Price: ৳ 3.50 (3 x 10: ৳ 105.00)
Strip Price: ৳ 35.00

Medicine Details

Category Details
Generic Sodium valproate
Company Unimed unihealth pharmaceuticals ltd
Also available as
Eval 250 mg syrup Eval cr 200 mg tablet Eval cr 300 mg tablet Eval cr 500 mg tablet

Indications

  • Treatment of all types of epilepsy
  • Treatment of bipolar disorder
  • Prophylaxis of migraine

Composition

  • Sodium Valproate tablet 200mg
  • Sodium Valproate syrup 200mg/5ml
  • Sodium Valproate controlled release 200 tablet
  • Sodium Valproate controlled release 300 tablet
  • Sodium Valproate controlled release 500 tablet
  • Sodium Valproate injection 500mg/5ml

Pharmacology

  • Anti-epileptic activity
  • Increase brain levels of gamma-aminobutyric acid (GABA)

Dosage & administration

  • Range of dosage for adults for epilepsy
  • Range of dosage for children for epilepsy
  • Dosage for bipolar disorder
  • Dosage for prophylaxis of migraine
  • Dosage for injection in adults
  • Dosage for injection in children

Interaction

  • Non-specific inhibitor of drug metabolism
  • Significant interactions with Phenobarbital, Phenytoin, Warfarin, Aspirin

Contraindications

  • Hypersensitivity to the drug
  • Liver dysfunction
  • Restricted use during pregnancy and in women of childbearing potential

Side effects

  • Common side effects: anorexia, nausea, vomiting
  • CNS effects: sedation, ataxia, tremor
  • Other effects: rash, alopecia, stimulation of appetite
  • Hepatic function effects: elevation of liver enzymes, fulminate hepatitis
  • Prone to suffer from hepatic injury, acute pancreatitis, hyperammonemia

Pregnancy & lactation

  • Crosses the placenta
  • Associated with neural tube defects in newborns
  • Excreted in breast milk
  • No risk to the child from breast-feeding mothers

Precautions & warnings

  • Monitoring of liver functions
  • Check for potential bleeding before surgery
  • Care in renal impairment, pregnancy, breast-feeding, and systemic lupus erythematosus
  • Partially eliminated in the urine as a ketone metabolite
  • Avoid sudden withdrawal of therapy

Therapeutic class

  • Primary anti-epileptic drugs

Storage conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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