Propranol 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Propranolol hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Cardiac arrhythmia
- Thyrotoxicosis
- Anxiety
- Prophylaxis of migraine
Pharmacology
Propranolol Hydrochloride is a B-adrenergic receptor blocking drug which is widely used in hypertension and angina pectoris. Propranolol antagonizes catecholamines at B-adrenergic receptors, thus prevents excess rate and force of contraction of the heart and decreases the excess consumption of oxygen by the heart.
Dosage & Administration
- Adult (above 18 years): Initially 80 mg twice daily, may be increased at weekly intervals and then maintenance dose of 160-320 mg daily is recommended.
- Child (From day 1 to 18 years): Hypertension: Neonate: 0.25-0.5 mg/kg 3 times daily, adjusted according to response. Child 1 month-12 years: 0.25-1 mg/kg 3 times daily, maximum dose 5 mg/kg daily in divided dose. Child 12-18 years: initially 80 mg twice daily, maintain 160-320 mg daily.
Interaction
Patients receiving verapamil, salbutamol, Levosalbutamol, ergot alkaloids, lidocain, phenobarbital drugs should be closely observed during therapy.
Contraindications
Bronchospasm, cardiogenic shock, second or third degree heart block, diabetes mellitus, etc.
Side Effects
- Cold extremities
- Lassitude
- Nausea
- Dizziness
- Insomnia
- Paresthesia
Pregnancy & Lactation
Pregnancy category C, should not be used in pregnant women. Propranolol is excreted in human milk. Caution should be taken when propranolol is administered to a nursing mother.
Precautions & Warnings
It should be taken with caution in hepatic and renal impairment, pregnancy, and lactating mother.
Therapeutic Class
Beta-adrenoceptor blocking drugs, Beta-blockers
Storage Conditions
Store in a cool and dry place, protected from light.