Gastalfet 1000 mg (Tablet)

Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Sucralfate
Company Beximco pharmaceuticals ltd
Also available as
Gastalfet 500 mg tablet Gastalfet 1 gm suspension

Indications

  • Duodenal ulcer
  • Gastric ulcer
  • Chronic gastritis
  • Prophylaxis of gastrointestinal hemorrhage from stress ulceration in seriously ill patients

Pharmacology

  • Non-systemic drug
  • Minimally absorbed from the gastrointestinal tract
  • Promotes healing of gastric and duodenal ulcers
  • Forms a protective barrier at the ulcer site
  • Inhibits the action of pepsin and bile

Dosage

  • Usual dose for adults: 2 gm of Sucralfate twice daily or 1 gm four times a day
  • Maximum daily dose is 8 gm
  • Pediatric population: Safety and efficacy not established
  • Elderly: No special dosage requirements
  • Prophylaxis of stress ulceration: 1 gm orally or via a nasogastric tube, 4 to 6 times a day

Administration

  • Take on an empty stomach
  • Do not administer with antacids within 30 minutes

Interaction

  • May reduce bioavailability of certain drugs
  • Potential interactions with Fluoroquinolones, Tetracycline, Ketoconazole, Sulpiride, Digoxin, Warfarin, Phenytoin, Theophylline, Levothyroxine, Quinidine, and H2 antagonists
  • Should not be co-administered with citrate preparations
  • Separate administration from other agents if critical for bioavailability

Contraindications

  • Patients with hypersensitivity to sucralfate

Side Effects

  • Common adverse events: headache, nausea, abdominal pain, constipation, diarrhea, urticaria
  • Bezoar formation with underlying medical conditions or concomitant enteral tube feedings
  • Episodes of hyperglycemia reported in diabetic patients

Pregnancy & Lactation

  • Safety not established in pregnant women
  • Use during pregnancy only if clearly needed
  • Caution when administered to breastfeeding women

Precautions & Warnings

  • Caution in patients with renal dysfunction
  • Not recommended for use in individuals on dialysis
  • Extreme caution in severe or chronic renal impairment
  • Periodic laboratory testing recommended for patients with impaired renal function
  • Bezoars reported mainly in severely ill patients in intensive care units

Use in Special Populations

  • Not recommended for use in children under 14 years of age
  • Dose adjustments not necessary in elderly patients
  • Use with caution in renal insufficiency patients
  • Patients should not drive if feeling dizzy or drowsy

Overdose Effects

  • Most cases of overdose remained asymptomatic
  • Symptoms may include abdominal pain, nausea, vomiting
  • Minimal risks associated with overdose

Therapeutic Class

  • Chelating complex

Storage Conditions

  • Store in a cool and dry place
  • Protect from light

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