Gastalfet 1000 mg (Tablet)
Unit Price: ৳ 6.00 (10 x 10: ৳ 600.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sucralfate |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Duodenal ulcer
- Gastric ulcer
- Chronic gastritis
- Prophylaxis of gastrointestinal hemorrhage from stress ulceration in seriously ill patients
Pharmacology
- Non-systemic drug
- Minimally absorbed from the gastrointestinal tract
- Promotes healing of gastric and duodenal ulcers
- Forms a protective barrier at the ulcer site
- Inhibits the action of pepsin and bile
Dosage
- Usual dose for adults: 2 gm of Sucralfate twice daily or 1 gm four times a day
- Maximum daily dose is 8 gm
- Pediatric population: Safety and efficacy not established
- Elderly: No special dosage requirements
- Prophylaxis of stress ulceration: 1 gm orally or via a nasogastric tube, 4 to 6 times a day
Administration
- Take on an empty stomach
- Do not administer with antacids within 30 minutes
Interaction
- May reduce bioavailability of certain drugs
- Potential interactions with Fluoroquinolones, Tetracycline, Ketoconazole, Sulpiride, Digoxin, Warfarin, Phenytoin, Theophylline, Levothyroxine, Quinidine, and H2 antagonists
- Should not be co-administered with citrate preparations
- Separate administration from other agents if critical for bioavailability
Contraindications
- Patients with hypersensitivity to sucralfate
Side Effects
- Common adverse events: headache, nausea, abdominal pain, constipation, diarrhea, urticaria
- Bezoar formation with underlying medical conditions or concomitant enteral tube feedings
- Episodes of hyperglycemia reported in diabetic patients
Pregnancy & Lactation
- Safety not established in pregnant women
- Use during pregnancy only if clearly needed
- Caution when administered to breastfeeding women
Precautions & Warnings
- Caution in patients with renal dysfunction
- Not recommended for use in individuals on dialysis
- Extreme caution in severe or chronic renal impairment
- Periodic laboratory testing recommended for patients with impaired renal function
- Bezoars reported mainly in severely ill patients in intensive care units
Use in Special Populations
- Not recommended for use in children under 14 years of age
- Dose adjustments not necessary in elderly patients
- Use with caution in renal insufficiency patients
- Patients should not drive if feeling dizzy or drowsy
Overdose Effects
- Most cases of overdose remained asymptomatic
- Symptoms may include abdominal pain, nausea, vomiting
- Minimal risks associated with overdose
Therapeutic Class
- Chelating complex
Storage Conditions
- Store in a cool and dry place
- Protect from light