Ucrafate 1 gm/5 ml (Oral Suspension)

200 ml bottle: ৳ 400.00

Medicine Details

Indications

  • Treatment of duodenal ulcer
  • Treatment of gastric ulcer
  • Treatment of chronic gastritis
  • Prophylaxis of gastrointestinal hemorrhage

Pharmacology

  • Non-systemic drug
  • Minimally absorbed from gastrointestinal tract
  • Promotes healing of ulcers by forming chemical complex at ulcer site
  • Inhibits action of pepsin and bile

Dosage

  • Usual dose for adults: 2gm twice daily or 1gm four times a day
  • Maximum daily dose for resistant cases: 8gm
  • Pediatric population: Safety and efficacy not established
  • Elderly: No special dosage requirements

Administration

  • Take on an empty stomach
  • Do not administer antacids within 30 minutes

Interaction

  • May reduce bioavailability of certain drugs
  • Bioavailability restoration by separating administration from Ucrafate by two hours
  • Should not be co-administered with citrate preparations

Contraindications

  • Contraindicated in patients with hypersensitivity to sucralfate

Side Effects

  • Common adverse events: headache, nausea, abdominal pain, constipation, diarrhea, urticaria
  • Bezoar formation reported in some cases
  • Episodes of hyperglycemia reported in diabetic patients

Pregnancy & Lactation

  • Safety in pregnant women not established
  • Caution in breastfeeding women

Precautions & Warnings

  • Use with caution in patients with renal dysfunction
  • Not recommended for individuals on dialysis
  • Laboratory testing recommended for patients with impairment of renal function
  • Concomitant use of other aluminium containing medications not recommended
  • Bezoars reported in severely ill patients

Use in Special Populations

  • Not recommended for use in children under 14 years of age
  • No dose adjustments necessary for elderly patients
  • Use with caution in renal insufficiency patients
  • Effects on ability to drive and use machines: Patients should not drive if feel dizzy or drowsy

Overdose Effects

  • Most cases remain asymptomatic
  • Symptoms may include abdominal pain, nausea, and vomiting in some cases

Therapeutic Class

  • Chelating complex

Storage Conditions

  • Store in a cool and dry place
  • Protected from light

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