Ancor 5 mg (Tablet)

Unit Price: ৳ 11.50 (3 x 10: ৳ 345.00)
Strip Price: ৳ 115.00

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Aristopharma ltd
Also available as
Ancor 25 mg tablet Ancor 10 mg tablet

Title

Ancor 5 mg Tablet

Categories

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Description

Ancor 5 mg Tablet is a beta-blocker medication. Beta-blockers work by blocking the effects of adrenaline. Ancor 5 mg Tablet helps to lower blood pressure, reduce the workload on the heart, and prevent chest pain.

Indication

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Pharmacology

Bisoprolol Hemifumarate is the most selective ß1 blocker. It displays highest level of affinity for the ß1 receptor than any other beta-blocker available up to now. Selectively blocks ß1 adrenergic receptor in the heart and vascular smooth muscle and reduces heart rate and cardiac output resulting in decrease of arterial hypertension.

AbsorptionBioavailability

Bisoprolol is almost completely (>90%) absorbed from the gastrointestinal tract.

Distribution

Bisoprolol is extensively distributed.

Metabolism

Bisoprolol is metabolized via oxidative pathways with no subsequent conjugation.

Elimination

The clearance of Bisoprolol is balanced between renal elimination of the unchanged molecule (-50%) and hepatic metabolism (-50%) to metabolites which are also renally excreted.

DosageAdministration

  • Adult:
    • Starting dose: 5 mg once daily
    • Usual dose range: 5-20 mg once daily
  • Children: Safety and effectiveness not established.
  • RenalHepaticImpairment:
    • Initial daily dose should be 5 mg
    • Use caution in dose titration

Interactions

  • BetaBlockingAgents: Should not be combined with other ß-blocking agents.
  • CatecholamineDepletingDrugs: Patients receiving catecholamine-depleting drugs should be monitored closely.
  • CentrallyActiveAntihypertensiveAgents: ß-blockers may exacerbate the rebound hypertension which can follow the withdrawal of clonidine.
  • AntiarrhythmicAgents: Should be used with care when myocardial depressants or inhibitors of A-V conduction are used concurrently.
  • CalciumChannelBlockers: Combined use with negative inotropic effects can lead to prolongation of S-A and A-V conduction.

Contraindications

In patients with cardiogenic shock, overt heart failure, second or third degree A-V block, right ventricular failure secondary to pulmonary hypertension and sinus bradycardia.

SideEffects

  • Fatigue
  • Dizziness
  • Headache
  • Disturbances of the gut
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties due to bronchospasm

PregnancyLactation

  • Pregnancy: Bisoprolol fumarate should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
  • Lactation: It is not known whether this drug is excreted in human milk. If use of bisoprolol fumarate is considered essential, then mothers should stop nursing.

PrecautionsWarnings

Use caution in adjusting the dose of Ancor in patients with renal or hepatic impairment.

TherapeuticClass

Anti adrenergic agent (Beta blockers)

StorageConditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

ChemicalStructure

  • MolecularFormula: C18H31NO4
  • ChemicalStructureImageURL: https://medex.com.bd/storage/res/g-res-135-bisoprolol-hemifumarate-chemical-structure-rpXCAgy2GIOFKWUs5Peu.svg

CommonlyAskedQuestions

  • WhatIsItUsedFor: Ancor 5 mg Tablet is used to make your heart beat slower and your blood vessels wider. It's a medication for High blood pressure (hypertension), Chest pain (angina), and Heart failure.
  • HowToTake: You should take Ancor 5 mg Tablet by mouth, with or without food, once daily.
  • SideEffects: Ancor 5 mg Tablet can have several side effects, including: Dizziness, Fatigue, Headache, Slow heart rate, Difficulty breathing, and Cold hands and feet.
  • SafeToTake: Ancor 5 mg Tablet is generally safe to take, but you should talk to your doctor before taking it if you have any health conditions.
  • StorageAndDisposalInstructions: Ancor 5 mg Tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

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