Penfil 10 mg (Tablet)

Unit Price: ৳ 30.00 (1 x 4: ৳ 120.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Tadalafil
Company Biopharma limited
Also available as

Indications

  • Erectile Dysfunction (ED)
  • Benign Prostatic Hyperplasia (BPH)
  • Both ED and BPH

Pharmacology

Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor. Inhibition of PDE5 increases cGMP in smooth muscle cells, causing penile erection and smooth muscle relaxation in the prostate and bladder.

Dosage & Administration

  • Starting dose: 10 mg for ED
  • Recommended dose: 5 mg for BPH
  • Maximum dosing frequency: once daily
  • Effective duration: up to 36 hours

Interaction

  • Nitrates
  • Alpha adrenergic blockers
  • Antihypertensives
  • Alcohol
  • Antacids
  • Ketoconazole
  • Ritonavir
  • Erythromycin
  • Itraconazole
  • Grapefruit juice
  • HIV protease inhibitors
  • Rifampin
  • Carbamazepine
  • Phenytoin
  • Phenobarbital

Contraindications

  • Use of Nitrates
  • Hypersensitivity reactions to Tadalafil

Side Effects

  • Headache
  • Dyspepsia
  • Back pain
  • Myalgia
  • Nasal pharyngitis
  • Nasal congestion
  • Change in Color Vision
  • Sudden vision loss
  • Hearing loss
  • Stevens-Johnson Syndrome
  • Exfoliative dermatitis
  • Angina
  • Stroke
  • Myocardial infarction
  • Severe hypotension
  • Tachycardia

Pregnancy & Lactation

Category B for pregnancy; caution during lactation

Precautions & Warnings

  • Angina
  • Renal impairment
  • Hepatic impairment
  • Bleeding concomitant with Nitrates
  • Alpha Blockers
  • Alcohol
  • CYP3A4 Inhibitors
  • Other PDE5 inhibitors

Therapeutic Class

Drugs for Erectile Dysfunction

Storage Conditions

Dry place, away from light and heat, keep out of reach of children

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