Penfil 10 mg (Tablet)
Unit Price: ৳ 30.00 (1 x 4: ৳ 120.00)
Strip Price: ৳ 120.00
Medicine Details
Category | Details |
---|---|
Generic | Tadalafil |
Company | Biopharma limited |
Also available as |
Indications
- Erectile Dysfunction (ED)
- Benign Prostatic Hyperplasia (BPH)
- Both ED and BPH
Pharmacology
Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor. Inhibition of PDE5 increases cGMP in smooth muscle cells, causing penile erection and smooth muscle relaxation in the prostate and bladder.
Dosage & Administration
- Starting dose: 10 mg for ED
- Recommended dose: 5 mg for BPH
- Maximum dosing frequency: once daily
- Effective duration: up to 36 hours
Interaction
- Nitrates
- Alpha adrenergic blockers
- Antihypertensives
- Alcohol
- Antacids
- Ketoconazole
- Ritonavir
- Erythromycin
- Itraconazole
- Grapefruit juice
- HIV protease inhibitors
- Rifampin
- Carbamazepine
- Phenytoin
- Phenobarbital
Contraindications
- Use of Nitrates
- Hypersensitivity reactions to Tadalafil
Side Effects
- Headache
- Dyspepsia
- Back pain
- Myalgia
- Nasal pharyngitis
- Nasal congestion
- Change in Color Vision
- Sudden vision loss
- Hearing loss
- Stevens-Johnson Syndrome
- Exfoliative dermatitis
- Angina
- Stroke
- Myocardial infarction
- Severe hypotension
- Tachycardia
Pregnancy & Lactation
Category B for pregnancy; caution during lactation
Precautions & Warnings
- Angina
- Renal impairment
- Hepatic impairment
- Bleeding concomitant with Nitrates
- Alpha Blockers
- Alcohol
- CYP3A4 Inhibitors
- Other PDE5 inhibitors
Therapeutic Class
Drugs for Erectile Dysfunction
Storage Conditions
Dry place, away from light and heat, keep out of reach of children