Bislol 2.5 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 14: ৳ 294.00)
Strip Price: ৳ 98.00

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Opsonin pharma ltd
Also available as
Bislol 5 mg tablet Bislol 10 mg tablet Bislol 125 mg tablet

Indications

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Pharmacology

  • Selective ß1 blocker
  • Reduced heart rate
  • Decrease of arterial hypertension
  • No adverse effect on cholesterol fraction
  • High absorption rate
  • Almost complete absorption from gastrointestinal tract
  • Extensive distribution
  • Metabolized via oxidative pathways
  • Balanced clearance between renal elimination and hepatic metabolism
  • Elimination half-life of 10-12 hours

Dosage & Administration

  • Usual starting dose of 5 mg once daily for adults
  • Increased to 10 mg and then to 20 mg once daily if necessary
  • Appropriate titration interval of 2 weeks
  • Initial daily dose of 5 mg for patients with renal or hepatic impairment
  • No need to adjust dose in the elderly unless significant renal or hepatic dysfunction
  • Safety and effectiveness not established in children

Interaction

  • Not to be combined with other β-blocking agents
  • Careful monitoring with catecholamine-depleting drugs
  • Exacerbation of rebound hypertension with centrally active antihypertensive agents
  • Caution with myocardial depressants or inhibitors of A-V conduction
  • Potential severe hypotension, bradycardia, and cardiac failure with combined use of β-blockers and calcium channel blockers

Contraindications

  • Cardiogenic shock
  • Overt heart failure
  • Second or third degree A-V block
  • Right ventricular failure secondary to pulmonary hypertension
  • Sinus bradycardia

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Disturbances of the gut such as nausea, vomiting, diarrhea, constipation, or abdominal pain
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties due to a narrowing of the airways (bronchospasm) in people with asthma or COPD

Pregnancy & Lactation

  • No teratogenic effects observed in rats at recommended human daily doses
  • Potential benefit justifies potential risk to the fetus in pregnancy
  • Small amounts detected in the milk of lactating rats

Precautions & Warnings

  • Use caution in adjusting the dose in patients with renal or hepatic impairment
  • Patients with a history of severe anaphylactic reaction may be more reactive to repeated challenge
  • Unresponsive to usual doses of epinephrine

Therapeutic Class

  • Anti adrenergic agent (Beta blockers)
  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula : C<sub>18</sub>H<sub>31</sub>NO<sub>4</sub>

Common Questions about Bislol 2.5 mg Tablet

  • Beta-blocker medication
  • Used to lower blood pressure, reduce workload on the heart, and prevent chest pain
  • Should be taken by mouth, with or without food, once daily
  • Common side effects include dizziness, fatigue, headache, slow heart rate, difficulty breathing, and cold hands and feet
  • Should be used with caution in patients with asthma, diabetes, heart problems, liver or kidney problems, low blood pressure, and depression

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