Prostacin D 0.4 mg+0.5 mg (Capsule)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tamsulosin hydrochloride dutasteride |
| Company | Incepta pharmaceuticals ltd |
Indications
- Moderate to severe symptoms of benign prostatic hyperplasia (BPH)
- Reduction in risk of acute urinary retention and surgery
Pharmacology
- Combination of Tamsulosin Hydrochloride and Dutasteride
- Mechanism of action to improve BPH symptoms
- Alpha1A-adrenoreceptor antagonist
- Dual 5 alpha reductase inhibitor
- Improvement in urine flow rate
- Reduction in BPH symptoms
Dosage & Administration
- One capsule daily
- Tamsulosin Hydrochloride 0.4 mg & Dutasteride 0.5 mg per capsule
- Orally, after a meal
- Swallow whole, not chewed or opened
- Renal and hepatic impairment considerations
Interaction
- No drug interaction studies
- Effects on Dutasteride pharmacokinetics
- Effects of Dutasteride on other drugs
- Caution with concomitant medications
- PDE5 inhibitors, alpha-1 adrenergic blockers interactions
Contraindications
- Contra-indicated in women, children, hypersensitivity
- Hypersensitivity to Dutasteride or Tamsulosin
- History of orthostatic hypotension
- Severe hepatic impairment
Side Effects
- Impotence
- Decreased libido
- Breast disorders
- Ejaculation disorders
- Dizziness
Pregnancy & Lactation
- Contra-indicated for women
- Affects male fertility
- Inhibits development of external genitalia
- No studies on pregnancy, lactation effects
Precautions & Warnings
- Careful benefit-risk assessment needed
- Increased risk of adverse events
- Cardiac failure caution
- Effects on prostate specific antigen (PSA)
- Prostate cancer detection precautions
Overdose Effects
- No data for Tamsulosin-Dutasteride combination
- High doses of Dutasteride and Tamsulosin effects
- Symptomatic and supportive treatment for over dosage
Therapeutic Class
- BPH/ Urinary retention/ Urinary incontinence
Storage Conditions
- Cool and dry place
- Protected from light