Telma 40 mg (Tablet)
Unit Price: ৳ 12.50 (3 x 10: ৳ 375.00)
Strip Price: ৳ 125.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Telmisartan |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of essential hypertension in adults
- Reduction of cardiovascular morbidity in adults with atherothrombotic cardiovascular disease or type 2 diabetes mellitus with documented target organ damage
Pharmacology
- Non-peptide angiotensin-ll receptor antagonist
- Blocks vasoconstrictor and aldosterone-secreting effects of angiotensin-ll
- Selective binding to AT1 receptor in vascular smooth muscle and adrenal gland
- Does not inhibit ACE (kininase-ll)
Dosage & Administration
- Usual starting dose of 40 mg once a day
- Blood pressure response is dose-related
- Maximal reduction generally attained after 4 weeks
- May be administered with other antihypertensive agents
- No initial dosage adjustment for elderly patients or patients with renal impairment
- Not recommended for patients ≥75 years old or with hepatic impairment
Pediatric use
- Safety and effectiveness not established
Geriatric use
- No overall differences in effectiveness and safety observed compared to younger patients
Hepatic impairment
- Monitor carefully and up titrate slowly in patients with biliary obstructive disorders or hepatic insufficiency
Interaction
- Increased risk of renal impairment and loss of antihypertensive effect with NSAIDS
- Co-administration with aliskiren in patients with diabetes should be avoided
Contraindications
- Known hypersensitivity to the product or any of its components
Side Effects
- Sinus pain and congestion, back pain, diarrhea
- Intermittent claudication and skin ulcer
Pregnancy & Lactation
- Pregnancy Category C (first trimester) and D (second and third trimester)
- Potential adverse effects on the nursing infant
- Consideration required for discontinuing nursing or the drug
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Hypotension
- Monitor carefully in patients with impaired hepatic or renal function
- Avoid concomitant use of an ACE inhibitor and angiotensin receptor blocker
Overdose Effects
- Manifestation would be hypotension, dizziness, tachycardia
- Bradycardia, increase in serum creatinine, acute renal failure
Therapeutic Class
- Angiotensin-ll receptor blocker
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children