Arbitel Plus 40 mg+12.5 mg (Tablet)

Unit Price: ৳ 12.50 (3 x 10: ৳ 375.00)
Strip Price: ৳ 125.00

Medicine Details

Category Details
Generic Telmisartan hydrochlorothiazide
Company Aci limited
Also available as

Indications

  • Treatment of hypertension
  • Lowering blood pressure
  • Reducing risk of cardiovascular events
  • Use alone or with other antihypertensive agents

Pharmacology

  • Telmisartan blocks AT1 receptor in many tissues
  • Hydrochlorothiazide is a thiazide diuretic
  • Increases plasma renin activity and aldosterone secretion
  • Reduces plasma volume
  • Mechanism of antihypertensive effect not fully understood

Dosage & Administration

  • Telmisartan monotherapy 80 mg once daily
  • Telmisartan and Hydrochlorothiazide 80 mg/12.5 mg once daily
  • Dose titration up to 160 mg/25 mg after 2 to 4 weeks if necessary
  • May be administered with other antihypertensive drugs

Interaction

  • Caution with aliskiren, digoxin, lithium, NSAIDs, corticosteroids, ACE blockers, angiotensin II receptor blockers
  • May interfere with certain laboratory tests

Contraindications

  • Known hypersensitivity to Telmisartan, Hydrochlorothiazide or any other component
  • Do not co-administer Aliskiren with diabetic patients

Side Effects

  • Dizziness
  • Drowsiness
  • Flushing
  • Back pain
  • Nausea
  • Diarrhea
  • Stomach pain
  • Elevations of liver enzymes
  • Leg cramps
  • Myalgia
  • Weakness
  • Gastric irritation
  • Photosensitivity

Pregnancy & Lactation

  • Pregnancy Category D
  • Discontinue use when pregnancy detected
  • Potential adverse effects on nursing infant

Precautions & Warnings

  • Caution with kidney disease, liver disease, dehydration, mineral imbalance, gout, diabetes
  • May affect blood sugar and body potassium levels
  • May cause dizziness
  • Report prolonged diarrhea or vomiting
  • Caution with the use of potassium supplements or salt substitutes containing potassium

Use in Special Populations

  • Pediatric use safety and effectiveness not established
  • Caution in dose selection for elderly patients
  • Initiate treatment under close medical supervision in patients with biliary obstructive disorders or hepatic insufficiency
  • Caution in patients with renal impairment

Overdose Effects

  • Hypertension
  • Dizziness
  • Tachycardia
  • Hypokalemia
  • Dehydration
  • Telmisartan not removed by hemodialysis
  • Degree of hydrochlorothiazide removal by hemodialysis not established

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep out of the reach of children
  • Keep in a cool and dry place
  • Protect from light

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