Telma Plus 40 mg+12.5 mg (Tablet)

Unit Price: ৳ 12.50 (3 x 10: ৳ 375.00)
Strip Price: ৳ 125.00

Medicine Details

Category Details
Generic Telmisartan hydrochlorothiazide
Company Beximco pharmaceuticals ltd

Indications

  • Treatment of hypertension
  • Lowering blood pressure
  • Reducing risk of cardiovascular events

Pharmacology

  • Blocking vasoconstrictor effects
  • Effects on aldosterone secretion
  • Renin-angiotensin system modulation
  • Selective AT1 receptor binding
  • Thiazide diuretic action
  • Electrolyte excretion
  • Plasma volume reduction
  • Plasma renin activity increase
  • Aldosterone secretion increase
  • Potassium loss reduction

Dosage & Administration

  • Initial dose of Telmisartan monotherapy 80 mg
  • Telmisartan/Hydrochlorothiazide 80 mg/12.5 mg once daily
  • Titration to 160 mg/25 mg if necessary
  • May be administered with other antihypertensive drugs

Interaction

  • Caution with aliskiren, digoxin, lithium
  • Interaction with other high blood pressure medicines
  • Possible interference with certain laboratory tests

Contraindications

  • Hypersensitivity to Telmisartan or Hydrochlorothiazide
  • Co-administration of Aliskiren in diabetic patients

Side Effects

  • Dizziness
  • Drowsiness
  • Flushing
  • Nausea
  • Diarrhea
  • Back pain
  • Elevations of liver enzymes
  • Leg cramps
  • Insomnia
  • Dry mouth
  • Chest pain
  • Leg pain
  • Allergy
  • Fever

Pregnancy & Lactation

  • Pregnancy Category D
  • Effects on fetal renal function
  • Potential adverse effects on neonate
  • Excretion in human milk
  • Possibility of adverse effects on nursing infant

Precautions & Warnings

  • Medical history considerations
  • Effect on blood sugar levels
  • Effect on body potassium levels
  • Impact on alertness and ability to operate machinery
  • Importance of adequate fluid intake

Use in Special Populations

  • Pediatric use not established
  • Geriatric patients dose selection caution
  • Close medical supervision for hepatic impairment
  • Severe renal impairment contraindicated

Overdose Effects

  • Manifestations of overdosage
  • Potential effects on electrolyte levels
  • Concerns related to hemodialysis

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep out of the reach of children
  • Store in a cool and dry place
  • Protection from light

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