Terbin 250 mg (Tablet)

Unit Price: ৳ 60.00 (1 x 10: ৳ 600.00)
Strip Price: ৳ 600.00

Medicine Details

Indications

  • Treatment of onychomycosis of the toenail or fingernail
  • Treatment of Tinea Capitis
  • Treatment of fungal infection of the skin caused by specific organisms
  • Treatment of tinea infections of the skin
  • Treatment of pityriasis (tinea) versicolor

Pharmacology

  • Inhibition of Ergosterol biosynthesis
  • Fungal cell death through increased membrane permeability
  • Activity against Tricophyton Mentagrophyte and Trichophyton Rubrum

Dosage & Administration

  • Oral administration of 250 mg tablet daily for 6-12 weeks
  • Granules dosage based on body weight
  • Topical cream application once or twice daily for specific durations
  • Spray application once or twice daily for specific durations

Interaction

  • Inhibition of the CYP450 2D6 isozyme
  • Potential interaction with specific drug classes

Contraindications

  • Hypersensitivity to terbinafine

Side Effects

  • Gastrointestinal symptoms
  • Liver test abnormalities
  • Rashes
  • Urticaria
  • Pruritus
  • Taste disturbances
  • Idiosyncratic and symptomatic hepatic injury
  • Serious skin reactions
  • Severe neutropenia
  • Thrombocytopenia
  • Angioedema
  • Allergic reactions
  • Malaise
  • Fatigue
  • Vomiting
  • Arthralgia
  • Myalgia
  • Hair loss

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Presence in breast milk
  • Foetal toxicity and fertility studies in animals

Precautions & Warnings

  • Risk of liver failure, skin reactions
  • External use for cream
  • Not recommended for patients with chronic or active liver disease

Use in Special Populations

  • Safety and efficacy not established in pediatric patients
  • No evidence of different dosages or side-effects in the elderly

Overdose Effects

  • Limited clinical experience
  • Symptoms include nausea, vomiting, abdominal pain, dizziness

Therapeutic Class

  • Other Antifungal preparations
  • Topical Antifungal preparations

Storage Conditions

  • Cool and dry place
  • Below 30°C
  • Protect from light

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