TC 250 mg (Capsule)
Unit Price: ৳ 1.00 (100's pack: ৳ 100.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Tetracycline hydrochloride oral |
| Company | Aztec pharmaceuticals ltd |
Indications
- Treatment of rickettsial infection
- Treatment of Mycoplasma pneumoniae infections in adults
- Treatment of Chlamydial Infections
- Treatment of non-gonococcal or non-specific urethritis
- Treatment of Lyme disease
- Treatment of brucellosis
- Treatment of granuloma inguinale
- Treatment of cholera
- Treatment of glanders
- Treatment of relapsing fever
- Treatment of V. vulnifians infections
- Treatment of urinary tract infections
- Treatment of bronchitis
- Treatment of pelvic inflammatory disease
- Treatment of travelers diarrhea
- Treatment of acne vulgaris
- Treatment of prostatitis
- Alternative agent in penicillin allergic patients with syphilis
- Treatment of anaerobic infections
- Oral dosage for adults
- Oral dosage for children
- Time of administration with or without meals
Pharmacology
- Mechanism of action on protein synthesis
- Active transport system for drug
- Binding to 30s ribosomes
- Inhibition of bacterial protein synthesis
- Susceptibility against Gram positive aerobic Cocci
- Resistance in staphylococci and streptococci
- Resistance in Pseudomonas and many Enterobacteriaceae
- Adequate urinary concentrations for E. coli
- Activity against anaerobic species of bacteria
- Absorption from the gastrointestinal tract
- Distribution in body tissues and fluids
- Half-life of about 12 hours
- Excretion in urine and feces
Dosage & Administration
- Usual adult oral dosage
- Oral dosage for children
- Dosage for acne vulgaris
- Dosage for acute staphylococcal infections
- Dosage for acute streptococcal infections
- Dosage for amoebiasis
- Dosage for brucellosis
- Dosage for subacute bacterial endocarditis
- Dosage for syphilis
Interaction
- Impaired absorption with antacids
- Interference with bactericidal action of penicillin
- Potentiation of anticoagulants
- Decrease in efficacy of oral contraceptives
- Exacerbation of nephrotoxic effects by diuretics
- Increase in hypoglycemic effect of insulin and sulfonylureas
- Increase in toxic effects of ergot alkaloids and methotrexate
Contraindications
- Hypersensitivity reactions
- Cross-sensitivity with tetracycline groups
- Systemic lupus erythematosus
- Renal impairment
Side Effects
- Depression of bone growth
- Teeth discoloration
- Enamel hypoplasia
- Hypersensitivity reactions
- Photosensitivity reactions
- Gastrointestinal effects
- Epigastric distress
- Accentuated prerenal azotemia
- Superinfections with oral and anogenital candidiasis
- Esophageal ulcerations
Pregnancy & Lactation
- Risk during pregnancy
- Risk during breastfeeding
- Impact on bone growth
- Impact on child's teeth
Precautions & Warnings
- Caution with impaired liver function
- Avoidance of high doses
- Avoidance of concomitant administration with potential hepatotoxic drugs
Therapeutic Class
- Belongs to Tetracycline group of drugs
Storage Conditions
- Recommended storage temperature