Bisopro 5 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Incepta pharmaceuticals ltd
Also available as
Bisopro 25 mg tablet

Indications

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Pharmacology

  • Selective ß1 blocker
  • Reduces heart rate
  • Decreases arterial hypertension
  • Minimal effect on lipid metabolism
  • Bisoprolol is almost completely absorbed from the gastrointestinal tract
  • Metabolized via oxidative pathways
  • Balanced clearance between renal elimination and hepatic metabolism
  • Elimination half-life of 10-12 hours

Dosage & Administration

  • Usual starting dose is 5 mg once daily
  • Dose may be increased to 10 mg and then to 20 mg once daily
  • Dosage must be individualized to the needs of the patient
  • Appropriate interval for dose titration is 2 weeks
  • Safety and effectiveness in children have not been established

Interaction

  • Not to be combined with other β-blocking agents
  • Patients receiving catecholamine-depleting drugs should be monitored closely
  • Exacerbates rebound hypertension with centrally active antihypertensive agents
  • Used with care when myocardial depressants or inhibitors of A-V conduction are used concurrently

Contraindications

  • Cardiogenic shock
  • Overt heart failure
  • Second or third degree A-V block
  • Right ventricular failure secondary to pulmonary hypertension
  • Sinus bradycardia

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Gastrointestinal disturbances
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties due to bronchospasm

Pregnancy & Lactation

  • Teratogenic in rats at high doses
  • Fetotoxic and embryolethal effects observed in animal studies
  • Use only if potential benefit justifies potential risk to the fetus
  • Small amounts detected in the milk of lactating rats

Precautions & Warnings

  • Use caution in adjusting the dose in patients with renal or hepatic impairment
  • Increased reactivity to allergens in patients with a history of severe anaphylactic reaction
  • Unresponsive to usual doses of epinephrine

Therapeutic Class

  • Anti adrenergic agent (Beta blockers)
  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C18H31NO4
  • Chemical Structure Image URL: <URL>

Common Questions about Bisopro 5 mg Tablet

  • Beta-blocker medication
  • Used for high blood pressure, chest pain, and heart failure
  • Should be taken by mouth once daily
  • Reported side effects include dizziness, fatigue, headache, slow heart rate, difficulty breathing, cold hands and feet
  • Safe use recommendations and storage instructions provided

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