Bisoren 2.5 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol hemifumarate |
| Company | Renata limited |
| Also available as |
Title
- Bisoren 2.5 mg Tablet
Categories
- Medicine
- Pharmacology
Description
- Bisoprolol is indicated for hypertension, angina, and moderate to severe heart failure
- It is a selective β1-blocker with high affinity for the β1 receptor
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Pharmacology
- High affinity for β1 receptor
- Reduces heart rate and cardiac output
- No change in cholesterol fraction including HDL-cholesterol
- High therapeutic reliability
- Bioavailability of 88%
- Metabolized via oxidative pathways
- Primarily metabolized via CYPSA4 with CYP2D6 having a minor role
- Elimination half-life of 10-12 hours
Dosage & Administration
- Starting dose of 5 mg once daily
- Max dose of 20 mg once daily
- Dose titration interval of 2 weeks
- Caution in patients with renal or hepatic impairment
- No need to adjust dose in the elderly unless significant renal or hepatic dysfunction
Interaction
- Not recommended with other β-blocking agents
- Monitor closely when combined with catecholamine-depleting drugs
- Use with care when used concurrently with centrally active antihypertensive agents, antiarrhythmic agents, or calcium channel blockers with negative inotropic effects
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side Effects
- Fatigue
- Dizziness
- Headache
- Gastrointestinal disturbances
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties
- Bronchospasm in people with asthma or COPD
Pregnancy & Lactation
- Not teratogenic in rats at doses up to 150 mg/kg/day
- Fetotoxic at 50 mg/kg/day and embryolethal at 12.5 mg/kg/day in rats
- No studies in pregnant women
- Small amounts detected in the milk of lactating rats
Precautions & Warnings
- Use caution in adjusting the dose in patients with renal or hepatic impairment
- Patients with severe anaphylactic reaction history may be more reactive to epinephrine
- Discuss use with doctor if having health conditions like asthma, diabetes, heart problems, liver or kidney problems, low blood pressure, or depression
Therapeutic Class
- Anti adrenergic agent (Beta blockers)
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C18H31NO4
- Chemical Structure image
Common Questions
- What is Bisoren 2.5 mg Tablet? - A beta-blocker medication
- What is it used for? - High blood pressure, Chest pain, and Heart failure
- How should it be taken? - By mouth, once daily
- What are the side effects? - Dizziness, Fatigue, Headache, Slow heart rate, Difficulty breathing, Cold hands and feet
- Is it safe to take? - Generally safe, but discuss with doctor based on health conditions
- Should it be taken empty stomach, before or after food? - After food
- Storage and disposal instructions
Quick Tips
- May cause dizziness, rise slowly from sitting or lying position
- Can hide symptoms of low blood sugar if diabetic, monitor sugar levels regularly
- Do not stop suddenly to avoid sudden rise in blood pressure