Theonate SR 300 mg (Tablet (Sustained Release))
Unit Price: ৳ 2.90 (40's pack: ৳ 116.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Theophylline |
| Company | Doctors chemical works ltd |
| Also available as |
Indications
- Control of acute asthma
- Management of chronic asthma (Symptomatic and prophylactic treatment)
- Management of chronic obstructive lung disease
- Control of apnea of pre-maturity
Pharmacology
- Bronchodilator
- Smooth muscle relaxation
- Diaphragmatic muscle contraction
- Half-life of Theophylline influenced by various variables
Dosage & Administration
- Individualized dose based on peak serum Theophylline concentration measurements
- Sustained release preparations may need administration every 12 hours in adults
- Recommended maintenance dose based on age
- Dosage adjustment for rapid hepatic metabolism
Interaction
- Contraindicated with other preparations containing xanthine derivatives
- Clearance influenced by various drugs
- Can potentiate hypokalemia resulting from beta-2-agonist therapy
Contraindications
- Hypersensitivity to Theophylline or any other component of the product
Side Effects
- Gastrointestinal discomfort
- Headache
- Nausea
- Insomnia
- Hypotension
- CNS stimulation
- Diuresis
Pregnancy & Lactation
- Not known whether Theophylline can cause fetal harm
- Should be given to pregnant women only if clearly needed
- Excreted into breast milk and may cause irritability in nursing infants
Precautions & Warnings
- Consideration needed for interacting drugs and physiologic conditions that can alter clearance
- Dosage adjustment required prior to initiation and during follow up
- Slow increase of dose if tolerated
Use in Special Populations
- Low clearance in neonates
- Dosage selection and monitoring required in pediatric patients
Therapeutic Class
- Bronchodilator
- Theophylline & related drugs
Storage Conditions
- Keep out of reach of children
- Store in a cool and dry place, protected from light