Thianomin 100 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 2.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Thiamine hydrochloride |
| Company | Rephco pharmaceuticals ltd |
Indications
- Treats thiamine deficiency such as Beriberi and Wernick's encephalopathy
- Neuritis associated with pregnancy
- Supplementary prophylactic treatment for low dietary intake or impaired absorption of thiamine
Pharmacology
- Thiamine pyrophosphate is the coenzyme for decarboxylation of α-ketoglutaric acid
- Necessary for optimal growth of infants and children
- Not stored in the body and is regularly lost during deficiency
- Deficiency leads to fatigue, anorexia, gastrointestinal disturbance, and neurological symptoms
Dosage administration
- Prophylaxis: 3 to 10 mg daily
- Mild chronic deficiency: 10 to 25 mg daily
- Severe deficiency: 200 to 300 mg daily
Interaction
- No hazardous drug interactions reported
- Acts synergistically with other B-complex vitamins
Contraindications
- Risk of anaphylaxis with repeated parenteral administration
- Mild allergic reactions may lead to anaphylactic shock
- Avoid intravenous administration except for comatose patients
Side effects
- No adverse effects when given orally
- Anaphylactic reactions may occur with large intravenous doses
- Transient mild soreness at intramuscular site
Pregnancy lactation
- Safe for neonates, children, pregnant and lactating women, and elderly patients
Therapeutic class
- Vitamin-B preparations
Storage conditions
- Should be protected from light and moisture