Ticoma DS 0.5% (Ophthalmic Solution)
5 ml drop: ৳ 70.26
Medicine Details
| Category | Details |
|---|---|
| Generic | Timolol maleate |
| Company | Opsonin pharma ltd |
Indications
- Treatment of elevated intraocular pressure
- Ocular hypertension
- Open-angle glaucoma
Pharmacology
- Non-selective β-adrenergic receptor blocker
- Reduction of aqueous humour formation
- Lowering of blood pressure
Dosage & Administration
- Initial dose of 0.25% solution bid
- Increase to 0.5% solution bid if inadequate response
- Decrease to 0.5% solution once daily if controlled
- Instill 1 drop of gel-forming eye drops once daily
Interaction
- Potential interaction with epinephrine
- Interactions with beta-adrenergic blocking agents, calcium antagonists, catecholamine-depleting drugs, digitalis, quinidine, clonidine, injectable epinephrine
Contraindications
- Bronchial asthma
- Severe chronic obstructive pulmonary disease
- Sinus bradycardia
- Second or third degree atrioventricular block
- Overt cardiac failure
- Cardiogenic shock
- Hypersensitivity to any component
Side Effects
- Burning and stinging sensation of the eyes
- Bradycardia
- Hypotension
- Arrhythmia
- CHF
- Pulmonary oedema
- Raynaud's phenomenon
- Headache
- Dizziness
- Fatigue
- Abdominal discomfort
- Nausea
- Constipation
- Hypoglycaemia
Pregnancy & Lactation
- Use during pregnancy only if potential benefit justifies potential risk to fetus
- Timolol detected in breast milk
- Potential for serious adverse reactions in nursing infants
Precautions & Warnings
- Inadequate cardiac function
- DM
- Myasthenia gravis
- Cerebrovascular insufficiency
- History of atopy
- Avoid abrupt withdrawal
- Patients undergoing major surgery
- May mask signs of hyperthyroidism and hypoglycaemia
- Should not be used as monotherapy for angle-closure glaucoma
- Renal and hepatic impairment
Overdose Effects
- Dizziness
- Headache
- Shortness of breath
- Bradycardia
- Bronchospasm
- Cardiac arrest
Therapeutic Class
- Drugs for miotics and glaucoma
Storage Conditions
- Store between 15-30° C
- Avoid freezing
- Protect from light