Ocupres 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 70.26

Medicine Details

Category Details
Generic Timolol maleate
Company Popular pharmaceuticals ltd

Indications

  • Treatment of elevated intraocular pressure
  • Indicated for ocular hypertension
  • Indicated for open-angle glaucoma

Pharmacology

  • Non-selective β-adrenergic receptor blocker
  • Reduction of aqueous humour formation
  • Lowers blood pressure

Dosage & Administration

  • Initial dose of 0.25% solution bid
  • May increase to 0.5% solution bid if inadequate response
  • Decrease to 0.5% solution once daily if controlled
  • Do not exceed 0.5% solution bid
  • Gel-forming eye drops: Instill 1 drop into the affected eye(s) once daily

Interaction

  • Potential interaction with epinephrine
  • Interactions with beta-adrenergic blocking agents
  • Interactions with calcium antagonists
  • Interactions with catecholamine-depleting drugs

Contraindications

  • Patients with bronchial asthma
  • Patients with severe chronic obstructive pulmonary disease
  • Patients with sinus bradycardia
  • Patients with second or third degree atrioventricular block
  • Patients with overt cardiac failure

Side Effects

  • Burning and stinging sensation of the eyes
  • Bradycardia
  • Hypotension
  • Arrhythmia
  • Headache
  • Dizziness
  • Fatigue
  • Abdominal discomfort
  • Nausea

Pregnancy & Lactation

  • Use during pregnancy if benefit justifies potential risk
  • Potential presence in breast milk
  • Consideration for nursing infants

Precautions & Warnings

  • Patients with inadequate cardiac function
  • Patients with DM
  • Patients with myasthenia gravis
  • Avoid abrupt withdrawal
  • Avoid in patients undergoing major surgery
  • Avoid monotherapy for angle-closure glaucoma

Overdose Effects

  • Reported systemic effects
  • Dizziness
  • Headache
  • Shortness of breath
  • Bronchospasm
  • Cardiac arrest

Therapeutic Class

  • Drugs for miotics and glaucoma

Storage Conditions

  • Store between 15-30° C
  • Protect from freezing
  • Protect from light

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