AL-DS 400 mg (Chewable Tablet)
Unit Price: ৳ 5.00 (10 x 4: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Globe pharmaceuticals ltd |
Title
AL-DS Anthelmintic Medicine
Categories
- Medicine
- Healthcare
- Anthelmintic
Description
AL-DS is a benzimidazole anthelmintic used in the treatment of intestinal nematode infections and in higher doses in the treatment of hydatid disease. It exhibits vermicidal, ovicidal, and larvicidal activity.
Indications
- Treatment of single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, and hydatid
Pharmacology
- Mode of action: Inhibitory effect on tubulin polymerization leading to the loss of cytoplasmic microtubules
- Mechanism: Blocking glucose uptake in susceptible helminths, leading to depletion of energy levels and subsequent immobilization
Dosage administration
- 400 mg as a single dose in cases of various worm infections
- 400 mg daily for 3 days in cases of strongyloidiasis or taeniasis
- 200 mg for children of 1-2 years as a single dose
- Not recommended for children under 1 year
- 400 mg twice daily for 28 days in patients weighing over 60 kg for hydatid disease
- 15 mg/kg body weight daily for patients weighing less than 60 kg in two divided doses, to a maximum total daily dose of 800 mg in hydatid disease
- 400 mg once daily for five days in giardiasis
Interactions
No reported pharmacodynamic or pharmacokinetic interactions
Contraindications
- Not used in neonates
- Dose reduction may be indicated in children weighing less than 10 kg
- Not recommended during pregnancy or in women thought to be pregnant
- No evidence to alter dose in renal, hepatic, or cardiac failure
Side effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia (rare)
- Rash
- Fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsion and meningism in cerebral disease
Pregnancy lactation
Should be avoided unless potential benefits outweigh the possible risks to the fetus
Precautions warnings
- Blood counts and liver function tests before and during treatment
- Caution during breastfeeding
- Exclude pregnancy before starting treatment
- Constant medical supervision and monitoring for Echinococcosis treatment
Therapeutic class
Anthelmintic
Storage conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children.