Anilic 200 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tolfenamic acid |
| Company | Drug international ltd |
Title
- Anilic 200 mg Tablet
Categories
- Pain Relief
- Migraine Treatment
- Fever Management
- NSAID
Description
- Anilic is a potent inhibitor of cyclooxygenase enzyme, used for relieving the pain of migraine headache, post-operative pain, and fever. It belongs to the fenamate group and is a potent inhibitor of cyclooxygenase enzyme, inhibiting the synthesis of important inflammatory mediators such as thromboxane (TX) B2 and prostaglandin (PG) E2.
Formulation
- Tablet
Dosage
200 mg
DosageInstructions
- 200 mg when symptoms appear may be repeated once after 1-2 hours for acute migraine attacks. 100-200 mg tid for mild to moderate pain. Dose adjustments may be needed for renal impairment, and it should be taken with food.
Indications
- Relieving the pain of migraine headache
- Analgesic for post-operative pain and fever
Pharmacology
- Inhibits cyclooxygenase enzyme
- Inhibits the synthesis of inflammatory mediators
- Direct antagonistic action on prostaglandin receptors
- Readily absorbed from the GI tract
- Protein-binding: 99%
- Plasma half-life: 2 hours
- Metabolized in the liver
- Excreted in urine (90%) and feces
Interaction
- Increased absorption with Metoclopramide and Magnesium hydroxide
- Decreased absorption with Aluminium hydroxide
- Risk of bleeding with anticoagulants and other NSAIDs
- Decreased antihypertensive response to loop diuretics, B-blockers, and ACE Inhibitors
- Increased plasma concentration of Lithium, Methotrexate, and cardiac glycosides
- Increased risk of nephrotoxicity with ACE inhibitors, Ciclosporin, Tacrolimus, or diuretics
Contraindications
- Active gastrointestinal bleeding
- Active gastrointestinal ulceration
- Severe heart failure
- History of gastrointestinal bleeding related to previous NSAID therapy
- History of gastrointestinal haemorrhage
- History of gastrointestinal perforation related to previous NSAID therapy
- History of recurrent gastrointestinal ulceration
SideEffects
- Rare alveolitis
- Hepatic damage
- Pancreatitis
- Pulmonary eosinophilia
- Stevens-johnson syndrome
- Angioedema
- Blood disorder
- Depression
- Diarrhea
- Dizziness
- Drowsiness
- Dysuria
- Euphoria
- Gastrointestinal bleeding
- Hallucination
- Insomnia
- Malaise
- Nausea
- Hearing disturbances
- Rash
- Visual disturbances
- Vertigo
- Raised blood pressure
PregnancyAndLactation
- Not recommended during pregnancy unless considered essential by a doctor
- Avoid use during the third trimester of pregnancy
- NSAIDs can appear in breast milk in very low concentrations
- NSAIDs should, if possible, be avoided when breastfeeding
PrecautionsAndWarnings
- Needed for patients with asthma bronchospasm, bleeding disorders, cardiovascular diseases, peptic ulceration, hypertension, liver infection, cardiac or renal function impairment, and elderly
- Increase water intake or dose reduction to reduce dysuria
OverdoseEffects
- Headache
- Nausea
- Vomiting
- Epigastric pain
- Gastrointestinal bleeding
- Diarrhea
- Excitation
- Coma
- Drowsiness
- Dizziness
- Tinnitus
- Fainting
- Convulsions
- Possible acute renal failure and liver damage
TherapeuticClass
- Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
- Other drugs for migraine
StorageConditions
- Store in a cool and dry place, away from light
- Keep out of the reach of children
ChemicalStructure
- Molecular Formula: C14H12ClNO2
CommonQuestions
- What is Anilic 200 mg Tablet?
- What are the uses of Anilic 200 mg Tablet?
QuickTips
- Anilic 200 mg Tablet should be taken with food or milk to avoid an upset stomach
- Can cause serious complications like stomach bleeding and kidney problems if taken for a long time
- Can raise the risk of blood clots, heart attack, or stroke
- Inform healthcare provider if pregnant, planning to conceive, breastfeeding, or have kidney or liver problems