Lucidol 100 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 20.00 (1 x 5: ৳ 100.00)

Medicine Details

Category	Details
Generic	Tramadol hydrochloride
Company	Beximco pharmaceuticals ltd
Also available as	Lucidol 50 mg capsule Lucidol 100 mg suppository

Indications

Postoperative pain
Colic and spastic pain
Cancer pain
Joint pain
Neck and back pain
Pain associated with osteoporosis

Pharmacology

Tramadol is a centrally acting synthetic analgesic compound that inhibits the reuptake of neurotransmitters- serotonin and noradrenaline. It modifies the transmission of pain impulses by activating serotonergic and noradrenergic pathways involved in analgesia.

Dosage & Administration

Capsule or Tablet: 50 to 100 mg every four to six hours for acute pain
Sustained Release Capsule & Tablet: One SR capsule or tablet every 12 hours
Injection: 50-100 mg every 4 to 6 hours
Suppository: 100 mg Tramadol Hydrochloride 6 hourly

The total daily dosage by mouth should not exceed 400 mg.

Interaction

Monoamine oxidase (MAO) inhibitors represent the only drug class not recommended for combination with Lucidol. Concomitant administration of carbamazepine with Lucidol causes a significant increase in Lucidol metabolism.

Contraindications

Hypersensitivity to Tramadol
Acute intoxication with alcohol, hypnotics, centrally acting analgesics, opioids, or psychotropic drugs

Side Effects

Dizziness/vertigo
Nausea
Constipation
Headache
Somnolence
Vomiting
Pruritus
CNS stimulation
Asthenia
Sweating
Dyspepsia
Dry mouth
Diarrhoea

Pregnancy & Lactation

Safe use of Tramadol in pregnancy has not been established. Tramadol has been shown to cross the placenta. Tramadol should not be administered during breastfeeding.

Precautions & Warnings

Respiratory depression may result from large doses of tramadol with anaesthetic medications or alcohol
Lucidol is not recommended for patients dependent on opioids
Caution advised when administering with CNS depressants such as alcohol, opioids, or sedative hypnotics
Use with caution in patients taking MAO inhibitors
Use with caution in patients with increased intracranial pressure, head injury, or acute abdominal conditions

Use in Special Populations

Children: Lucidol can be given in a dose of 1-2 mg/kg body weight for children from the age of 1 year
Adolescents: Suppository (100 mg Lucidol) should not be administered in children and adolescents below the age of 14 years

Therapeutic Class

Opioid analgesics

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children