Tenobis 5 mg (Tablet)
Unit Price: ৳ 10.05 (3 x 14: ৳ 422.10)
Strip Price: ৳ 140.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol hemifumarate |
| Company | Drug international ltd |
| Also available as |
Indications
- Hypertension
- Angina
- Moderate to severe heart failure
Pharmacology
- ß1 blocker
- Reduces heart rate
- Reduces cardiac output
- Decrease of arterial hypertension
- Minimal impact on lipid metabolism
- High therapeutic reliability
- High absorption rate
- Extensively distributed
- Metabolized via oxidative pathways
- Primarily metabolized via CYPSA4
- Balanced renal elimination and hepatic metabolism
- Long elimination half-life
Dosage & Administration
- Individualized dosage for hypertension
- Usual starting dose of 5 mg once daily
- Maximum dosage of 20 mg once daily
- Dose titration interval of 2 weeks
- Limited data for use in children and geriatrics
- Special dosage considerations for renal or hepatic impairment
Interaction
- Contraindicated with other β-blocking agents
- Closely monitor patients receiving catecholamine-depleting drugs
- Exercise caution with centrally active antihypertensive agents and antiarrhythmic agents
- Potential interaction with calcium channel blockers
Contraindications
- Cardiogenic shock
- Overt heart failure
- Second or third degree A-V block
- Right ventricular failure secondary to pulmonary hypertension
- Sinus bradycardia
Side Effects
- Fatigue
- Dizziness
- Headache
- Disturbances of the gut
- Cold or numb extremities
- Muscle weakness or cramps
- Breathing difficulties
- Bronchospasm in asthma patients
Pregnancy & Lactation
- Not teratogenic in rats at certain doses
- Fetotoxic and embryolethal in animal studies at high doses
- Use in pregnancy only if benefits outweigh risks
- Potential excretion in human milk
Precautions & Warnings
- Use caution in patients with renal or hepatic impairment
- Increased reactivity in patients with severe anaphylactic reaction
- Potential unresponsiveness to epinephrine
Therapeutic Class
- Anti adrenergic agent (Beta blockers)
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula : C18H31NO4
Common Questions about Tenobis 5 mg Tablet
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