Utramal 50 mg (Capsule)

Unit Price: ৳ 8.50 (3 x 10: ৳ 255.00)
Strip Price: ৳ 85.00

Medicine Details

Indications

  • Treatment of moderate to severe painful conditions
  • Postoperative pain
  • Colic and spastic pain
  • Cancer pain
  • Joint pain
  • Neck and back pain
  • Pain associated with osteoporosis

Pharmacology

  • Centrally acting synthetic analgesic compound
  • Inhibition of neurotransmitter reuptake
  • Mediation of pain impulses
  • Stimulation of mu-opioid receptors
  • Modulation of central monoaminergic inhibitory pathways

Dosage & Administration

  • Usual doses of 50 to 100 mg every 4-6 hours
  • Initial dose of 100 mg for acute pain
  • Initial dose of 50 mg for chronic painful conditions
  • Sustained release capsule or tablet administration every 12 hours
  • Injection dose of 50-100 mg every 4-6 hours
  • Suppository administration in adults

Interaction

  • Monoamine oxidase (MAO) inhibitors are not recommended for combination
  • Concomitant administration of carbamazepine increases Utramal metabolism

Contraindications

  • Hypersensitivity to the drug
  • Acute intoxication with alcohol, hypnotics, analgesics, opioids, or psychotropic drugs

Side Effects

  • Dizziness/vertigo
  • Nausea
  • Constipation
  • Headache
  • Somnolence
  • Vomiting
  • Pruritus
  • CNS stimulation
  • Asthenia
  • Sweating
  • Dyspepsia
  • Dry mouth
  • Diarrhea
  • Malaise
  • Allergic reaction
  • Weight loss
  • Vasodilatation
  • Palpitations
  • Abdominal pain
  • Anorexia
  • Flatulence
  • GI bleeding
  • Hepatitis
  • Stomatitis

Pregnancy & Lactation

  • Crosses the placenta
  • Use only if benefit justifies risk to the fetus
  • Not recommended during breastfeeding

Precautions & Warnings

  • Respiratory depression risk
  • Not recommended for opioid-dependent patients
  • Caution with CNS depressants
  • Caution in patients taking MAO inhibitors
  • Caution in patients with increased intracranial pressure or head injury, and acute abdominal conditions

Use in Special Populations

  • Can be given in children from the age of 1 year
  • Suppository not to be administered in children and adolescents below the age of 14 years
  • Utramal 100 mg SR Capsules not studied in children

Therapeutic Class

  • Opioid analgesics

Storage Conditions

  • Keep below 30°C temperature
  • Keep away from light & moisture
  • Keep out of reach of children

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