Block-T 500 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tranexamic acid |
| Company | Drug international ltd |
| Also available as |
Indications
- Prophylaxis and therapy of hemophtoes
- Digestive hemorrhages
- Hemorrhagic syndromes in leukaemia
- Cirrhosis and hemophilia
- Thrombocytopenic purpura
- Accidents during thrombolytic therapy and transfusion
- Prophylaxis and antihemorrhagic therapy during operations
- Prophylaxis and antihemorrhagic therapy of prostatic, vesical and renal surgery
- Prophylaxis and therapy of post-partum and puerperium hemorrhages
- Prophylaxis and antihemorrhagic therapy during a tonsillectomy
- Prophylaxis and antihemorrhagic therapy during maxillofacial operations
Pharmacology
- Strong antifibrinolytic action
- Inhibition of the plasminogen activation
- Well absorbed by oral route
- Excreted mainly by renal route
- Low acute toxicity
- Chronic toxicity almost non-existent
Dosage & Administration
- Usual dose for adults: 500-1000 mg 3 times daily
- Mean recommended daily doses for children: 0.5-1 gm orally, 500 mg by the parenteral route
Interaction
- Incompatible with solutions containing penicillins
- Thrombolytic drugs antagonize the antifibrinolytic action
- Increased potential for thrombus formation by estrogen-containing drugs
Contraindications
- Known individual hypersensitivity to the product
- Thromboembolic disease
- Arterial and venous thrombosis
- Serious kidney failure
Side Effects
- Sense of fatigue
- Conjunctival irritation
- Nasal blockage
- Itching
- Skin reddening
- Exanthems
- Nausea
- Diarrhea
- Gastric pyrosis
- Postural hypotension
Pregnancy & Lactation
- Tranexamic Acid should not be administered during known and presumed pregnancy
- Tranexamic Acid passes into breast milk to a concentration of approximately one hundredth of the concentration in the maternal blood
Precautions & Warnings
- Use in cases of hyperfibrinolysis
- Prophylactic treatment must begin 24 hours before the operation and continue until 3-4 days after it
- Therapy of hemorrhages must be prolonged for at least 24 hours after manifestations have disappeared
- Reduce doses in hematuria to prevent clot formation in the urinary tract
- Careful use in renal insufficiency, anuric syndromes, cardiopathic, and hepatopathic subjects
Therapeutic Class
- Anti-fibrinolytic drugs
- Haemostatic drugs
Storage Conditions
- Store in a dry place at 15-30°C
- Away from light
- Keep out of children's reach