Avidol 6.25 mg (Tablet)
Unit Price: ৳ 3.00 (6 x 10: ৳ 180.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Carvedilol |
| Company | Ad din pharmaceuticals ltd |
Title
- Avidol
Categories
- Medicine
- Cardiovascular drug
Description
- Indicated for the treatment of mild, moderate, or severe heart failure of ischemic or cardiomyopathic origin
- Used in conjunction with digitalis, diuretics, and ACE inhibitor to reduce the progression of disease
- May be used in patients unable to tolerate an ACE inhibitor
- May be used in patients who are not receiving digitalis, hydralazine, or nitrate therapy
- Main pharmacological action is non-selective antagonism of β-adrenergic receptors
Dimensions
- N/A
Color Options
- N/A
Functions
- Treatment of hypertension, angina pectoris, and congestive heart failure
- Antiproliferative properties
- Scavenger of reactive free oxidant radicals
Materials
- Carvedilol
Technical Specifications
- Initial dose of 12.5 mg once daily for hypertension
- Initial dose of 12.5 mg twice daily for angina pectoris
- Initial dose of 3.125 mg twice daily for heart failure
Design Elements
- N/A
Usability Features
- Increased monitoring of digoxin recommended when initiating, adjusting, or discontinuing the dose of Avidol
Dosage & Administration
- Initial dose of 12.5 mg once daily for hypertension
- Usual dose of 25 mg once daily for hypertension
- Maximum 50 mg daily dose for hypertension
- Initial dose of 12.5 mg twice daily for angina pectoris
- Recommended dosage of 25 mg twice daily for angina pectoris
- Maximum 50 mg daily dose for angina pectoris
- Initial dose of 3.125 mg twice daily for heart failure
- Titration to maximum 25 mg twice daily for heart failure in patients under 85 kg bodyweight
- Titration to maximum 50 mg twice daily for heart failure in patients over 85 kg bodyweight
Interaction
- Increased levels of digoxin with concomitant use
- Decrease in Cmax and AUC with pretreatment with rifampin
- No alteration in plasma protein binding of warfarin
- Potential potentiation of the pressor reaction when combined with clonidine
Contraindications
- Decompensated heart failure requiring intravenous inotropic therapy
- Bronchial asthma or related bronchospastic conditions
- Second or third-degree AV block
- Sick sinus syndrome (unless a permanent pacemaker is in place)
- Cardiogenic shock
- Severe bradycardia
Side Effects
- Postural hypotension
- Dizziness
- Headache
- Fatigue
- Gastro-intestinal disturbances
- Bradycardia
- Diminished peripheral circulation
- Peripheral edema
- Painful extremities
- Dry mouth
- Dry eyes
- Eye irritation
- Disturbed vision
- Impotence
- Disturbances of micturition
- Influenza-like symptoms
- Angina
- AV block
- Exacerbation of intermittent claudication or Raynaud's phenomenon
- Allergic skin reactions
- Exacerbation of psoriasis
- Nasal stuffiness
- Wheezing
- Depressed mood
- Sleep disturbances
- Paresthesia
- Changes in liver enzymes
- Thrombocytopenia
- Leukopenia
Pregnancy & Lactation
- Not recommended during breastfeeding
- No established safety and efficacy in children
- Not recommended during pregnancy
Precautions & Warnings
- Take caution in hepatic impairment
- Monitor clinical status for 2-3 hours after initiation and after increasing each dose
- Ensure that renal function and heart failure are not deteriorating before increasing dose
Therapeutic Class
- Alpha adrenoceptor blocking drugs
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep below 30°C temperature
- Keep away from light and moisture
- Keep out of the reach of children