Conatrim 1%+0.1% (Cream)
Medicine Details
| Category | Details |
|---|---|
| Generic | Econazole nitrate triamcinolone acetonide |
| Company | Ad din pharmaceuticals ltd |
Indications
- Eczematous Mycoses
- Psoriasis
- Tinea Pedis (Athlete’s foot)
- Tinea Corporis (Ring worm)
- Tinea Cruris (Jock itch)
- Inflammatory Intertrigo
- Diaper Dermatitis
- Onychomycoses
Composition
- Econazole Nitrate
- Triamcinolone Acetonide
Description
Broad spectrum antimycotic with anti-inflammatory, anti-pruritic and anti-allergic effects. Composed of Econazole Nitrate, a powerful antifungal and Triamcinolone Acetonide to enforce its antimicrobial effect and the effect of subduing comprehensive inflammations. Range of action covers all dermatomycoses caused by various pathogens.
Pharmacological Properties
Econazole Nitrate is only slightly absorbed from the skin. Triamcinolone Acetonide is well absorbed from sites of local application.
Dosage & Administration
- Adults: Applied sparingly to the skin lesion no more than 2 times daily, duration of treatment should continue until the inflammatory symptoms subside but not longer than 2 weeks.
- Pediatric Use: Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome.
Interaction
- Econazole: Metabolized by CYP3A4/2C9. Interacts with oral anticoagulants (warfarin & acenocoumarol).
- Triamcinolone: Lowers plasma salicylates levels. Increases risk of Gl bleeding and ulceration with NSAIDs.
Contraindications
- Hypersensitivity to any of its ingredients
- Specific skin conditions such as tuberculous, varicella, herpes simplex or other viral infections of the skin
- Fresh vaccination sites
- Decubitus ulcers
- Rosacea and rosacea-like dermatitis
Side Effects
- Transient local mild irritation
- Adrenal suppression on long term continuous topical steroid therapy, particularly in infants or children when occlusive dressings are applied
Pregnancy & Lactation
- Pregnancy: Topical steroids in large amounts or for prolonged periods should not be used.
- Lactation: This cream should not be prescribed to the lactating mother.
Precautions & Warnings
- For external use only
- Discontinue use if hypersensitivity or chemical irritation occurs
- Caution in children - should be used for short periods of time and on small areas
- Visual disturbance may be associated with systemic and topical corticosteroid use
Overdose Effects
In the event of accidental ingestion, treat symptomatically. If this cream is accidentally applied to the eyes, wash with clean water or saline and seek medical attention if symptoms persist.
Therapeutic Class
Triamcinolone & Combined preparations
Storage Conditions
Store in a cool (below 30°C) and dry place, away from light. Keep out of the reach of children.