Etriam 1%+0.1% (Cream)
10 gm tube: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Econazole nitrate triamcinolone acetonide |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Eczematous Mycoses
- Psoriasis
- Tinea Pedis (Athlete's foot)
- Tinea Corporis (Ring worm)
- Tinea Cruris (Jock itch)
- Inflammatory Intertrigo
- Diaper Dermatitis
- Onychomycoses
Description
- Broad spectrum antimycotic
- Anti-inflammatory
- Anti-pruritic
- Anti-allergic effects
- Composed of Econazole Nitrate
- Powerful antifungal
- Triamcinolone Acetonide
- Enforces antimicrobial effect
- Subdues comprehensive inflammations
- Covers all dermatomycoses caused by various pathogens
- Has antibacterial effect on gram-positive cocci and bacilli
Dosage & Administration
- Applied sparingly to the skin lesion
- No more than 2 times daily
- Preferably once in the morning and once in the evening
- Not to be applied with an occlusive dressing
- Duration of treatment should continue until the inflammatory symptoms subside but not longer than 2 weeks
- Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome
Interaction
- Econazole metabolized by CYP3A4/2C9
- Interacts with oral anticoagulants (warfarin & acenocoumarol)
- Triamcinolone can lower plasma salicylates levels
- Increased risk of gastrointestinal bleeding and ulceration with NSAIDs
- Antagonizes blood glucose-lowering effects of the antidiabetics
- Increased risk of Hyperkalemia with amphotericin B, beta-blockers, potassium-depleting diuretics, theophylline
- Increased clearance of triamcinolone with ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin
Contraindications
- Hypersensitivity to any of its ingredients
- Contraindicated in specific skin conditions such as tuberculous, varicella, herpes simplex or other viral infections of the skin, or fresh vaccination sites
- Decubitus ulcers
- Viral, bacterial or fungal skin infections
- Rosacea and rosacea-like dermatitis
Side Effects
- Transient local mild irritation
- Itching
- Redness
- Minimal allergenic effect
- Well tolerated, even by delicate skin
- Systemic effects including adrenal suppression
Pregnancy & Lactation
- Triamcinolone Acetonide crosses the placenta
- Topical administration of corticosteroids during pregnancy can cause abnormalities of foetal development
- Topical steroids in large amounts or for prolonged periods should not be used in pregnancy
- Negligible amount of econazole and to some extent Triamcinolone may be excreted in small amounts in breast milk
- Should not be prescribed to lactating mothers
Precautions & Warnings
- For external use only
- If a reaction suggesting hypersensitivity or chemical irritation should occur, use of the medication should be discontinued
- Corticosteroids applied to the skin can be absorbed in sufficient amounts to produce systemic effects
- Increased risk of dermatological superinfection or opportunistic infection
- Increased caution required when treating children
- Visual disturbance may be associated with systemic and topical corticosteroid use
Overdose Effects
- Corticosteroids applied to the skin can be absorbed in sufficient amounts to produce systemic effects
- In the event of accidental ingestion, treat symptomatically
- If accidentally applied to the eyes, wash with clean water or saline and seek medical attention
Therapeutic Class
- Triamcinolone
- Combined preparations
Storage Conditions
- Store in a cool (below 30°C) and dry place
- Away from light
- Keep out of the reach of children