Ecocort 1%+0.1% (Cream)

10 gm tube: ৳ 40.00

Medicine Details

Category	Details
Generic	Econazole nitrate triamcinolone acetonide
Company	Globe pharmaceuticals ltd

Indications

Eczematous Mycoses
Psoriasis
Tinea Pedis (Athlete's foot)
Tinea Corporis (Ring worm)
Tinea Cruris (Jock itch)
Inflammatory Intertrigo
Diaper Dermatitis

Onychomycoses Indication

Treatment of onychomycoses, local therapy with Econazole/Triamcinolone cream, combined with an oral antimycotic, is recommended.

Composition

Econazole Nitrate & Triamcinolone Acetonide

Broad Spectrum

Antifungal

Anti-inflammatory

Anti-pruritic

Anti-allergic

Effective Pathogens

Dermatophytes (e.g. Trichophyton)
Yeasts (e.g. Candida)
Moulds
Fungi (e.g. Histoplasma capsulatum)
Malassezia furfur
Nocardia minutissima

Antibacterial Effect

On gram-positive cocci and bacilli including Streptococcus pyogens and Staphylococcus aureus

Absorption

Econazole Nitrate: Slightly (<0.1%) absorbed from the skin
Triamcinolone Acetonide: Well absorbed from sites of local application

Dosage & Administration

Adults: Applied sparingly to the skin lesion no more than 2 times daily
Pediatric Use: Caution due to potential for greater susceptibility to topical corticosteroid-induced side effects

Interactions

Econazole: Metabolized by CYP3A4/2C9, interacts with oral anticoagulants (warfarin & acenocoumarol)
Triamcinolone: Interacts with various drugs such as NSAIDs, antidiabetics, amphotericin B, beta-blockers, and others

Contraindications

Hypersensitivity to any ingredients
Specific skin conditions (e.g. tuberculous, varicella, herpes simplex)
Decubitus ulcers
Rosacea and rosacea-like dermatitis

Side Effects

Transient local mild irritation
Itching & redness immediately after application
Adrenal suppression on long term continuous topical steroid therapy

Pregnancy & Lactation

Pregnancy: Topical administration of corticosteroids can cause abnormalities of foetal development
Lactation: Negligible amount of econazole and to some extent Triamcinolone may be excreted in breast milk

Precautions & Warnings

For external use only
Discontinue in case of hypersensitivity or chemical irritation
Caution for systemic effects due to absorption
Skin thinning and atrophy
Increased risk of dermatological superinfection or opportunistic infection
Visual disturbance may be associated with systemic and topical corticosteroid use

Overdose Effects

Corticosteroids applied to the skin can be absorbed in sufficient amounts to produce systemic effects