Angitrim MR 35 mg (Tablet (Modified Release))

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Trimetazidine dihydrochloride
Company Globe pharmaceuticals ltd

Indications

  • Add-on therapy for symptomatic treatment of stable angina pectoris in adults

Pharmacology

  • First 3-keto acyl CoA thiolase inhibitor (KAT)
  • Metabolic anti-ischemic agent
  • Inhibits fatty acid pathway
  • Transfers oxygen to glucose pathway
  • Aerobic oxidation of glucose stops production of lactic acid

Dosage & Administration

  • Recommended dose of 35 mg twice daily
  • Assess treatment benefit after three months
  • Discontinue if no treatment response

Interaction

  • No reported drug interaction
  • No interaction with beta-blockers, calcium antagonists, nitrates, heparin, hypolipidemic agents, or digitalis preparation

Contraindications

  • Hypersensitivity to the active substance or any excipients
  • Patients with Parkinson's disease or symptoms, tremors, restless legs movement disorders, severe renal impairment

Side Effects

  • Dizziness
  • Headache
  • Abdominal pain
  • Diarrhoea
  • Dyspepsia
  • Nausea
  • Vomiting
  • Rash
  • Pruritus
  • Urticaria
  • Asthenia

Pregnancy & Lactation

  • No data on use in pregnant women
  • Preferable to avoid use during pregnancy
  • Unknown excretion in human milk
  • Risk to newborns/infants cannot be excluded
  • Not recommended during breast-feeding

Precautions & Warnings

  • Not curative for angina attacks
  • Not an initial treatment for unstable angina pectoris
  • Not a treatment for myocardial infarction

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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