Carved 12.5 mg (Tablet)
Unit Price: ৳ 6.50 (3 x 10: ৳ 195.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Carvedilol |
| Company | Biopharma limited |
| Also available as |
Title and Categories
- Carvedilol
- Cardiovascular Drug
- Heart Failure Medication
- Hypertension Drug
- Angina Pectoris Medication
- Beta-blocker
Dimensions
Color Options
Functions
- Treatment of mild, moderate, or severe heart failure
- Reduction of cardiovascular death
- Reduction of cardiovascular hospitalization
- Hypertension treatment
- Angina pectoris treatment
- Non-selective antagonism of β-adrenergic receptors
Materials
Technical Specifications
- Initial dose of 12.5 mg once daily for hypertension
- Initial dose of 12.5 mg twice daily for angina pectoris
- Initial dose of 3.125 mg twice daily for heart failure
- Maximum dosage of 50 mg daily for hypertension
- Maximum dosage of 50 mg daily for angina pectoris
- Maximum dosage of 50 mg twice daily for heart failure
Design Elements
Usability Features
Interaction
- Increased levels of digoxin when taken together with Carvedilol
- Decrease in Cmax and AUC with pretreatment of rifampin
- No alteration of in vitro plasma protein binding of warfarin by Carvedilol
- Potential modification of pressure rise following the sudden withdrawal of treatment with clonidine
Contraindications
- Decompensated heart failure requiring intravenous inotropic therapy
- Bronchial asthma or related bronchospastic conditions
- Second or third-degree AV block
- Sick sinus syndrome without a permanent pacemaker
- Cardiogenic shock
- Severe bradycardia
Side Effects
- Postural hypotension
- Dizziness
- Headache
- Fatigue
- Gastrointestinal disturbances
- Bradycardia
- Diminished peripheral circulation
- Peripheral edema
- Dry mouth
- Dry eyes
- Eye irritation
- Impotence
- Disturbances of micturition
- Influenza-like symptoms
- Angina
- AV block
- Exacerbation of intermittent claudication
- Exacerbation of Raynaud's phenomenon
- Allergic skin reactions
- Exacerbation of psoriasis
- Nasal stuffiness
- Wheezing
- Depressed mood
- Sleep disturbances
- Paresthesia
- Heart failure
- Changes in liver enzymes
- Thrombocytopenia
- Leukopenia
Pregnancy & Lactation
- Not to be used during breastfeeding
- No established safety and efficacy in children
Precautions & Warnings
- Caution in hepatic impairment
- Monitor clinical status for 2-3 hours after initiation and increasing each dose
- Ensure renal function and heart failure are not deteriorating before increasing dose
Therapeutic Class
- Alpha adrenoceptor blocking drugs
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children