Ursodil 150 mg (Tablet)
Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ursodeoxycholic acid |
| Company | General pharmaceuticals ltd |
| Also available as |
Title
- Ursodil
Categories
- Medicine
- Pharmaceutical
Description
- Reduces cholesterol saturation of bile
- Promotes dissolution of gallstones
- Reduces cholesterol absorption
- Suppresses liver cholesterol synthesis
- Improves cholestatic liver diseases
Indications
- Cholestasis (Jaundice)
- Viral Hepatitis
- Alcoholic Fatty Liver
- Primary Billiary Cirrhosis (PBC)
- Primary Sclerosing Cholangitis (PSC)
- Dissolution of Gallstones
- Non-Alcoholic Steato Hepatitis (NASH)
Dosage & Administration
- Dissolution of Gallstones: 8-12 mg/kg/day
- Primary Billiary Cirrhosis: 10-15 mg/kg/day in 2-4 divided doses
- Acute Viral Hepatitis: 600 mg/day
- Alcoholic Fatty Liver: 300 mg/day
- Primary Sclerosing Cholangitis: 25-30 mg/kg/day
- Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis: 13-15 mg/kg/day
Pharmacology
- Naturally occurring bile acid
- Reduces cholesterol secretion in bile
- Promotes formation of liquid cholesterol crystal complexes
- Improves cholestatic liver diseases by protecting cholangiocytes and hepatocytes
- Completely absorbed in the upper intestine
- Biologic half-life ranges from 3.5-5.8 days
Interaction
- Avoid concomitant use with oestrogenic hormones
- Avoid concomitant use with bile-acid binding drugs
Contraindications
- Non-functioning gall-bladder
- Calcified and pigmented gallstones
- Inflammatory bowel disease
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Gallstone opacilication
- Pruritus
Pregnancy & Lactation
- Pregnancy category B
- No evidence of harm reported in pregnancy
- Effectively used for treatment of cholestasis of pregnancy during the last trimester
- No documented problems regarding breastfeeding
Precautions & Warnings
- Use cautiously in those with liver disease
Therapeutic Class
- Anti-gallstones drugs: Bile Acids
Storage Conditions
- Store below 25°C
- Protected from light and moisture
- Keep out of the reach of children