Ursodex 150 mg (Tablet)
Unit Price: ৳ 12.00 (4 x 10: ৳ 480.00)
Strip Price: ৳ 120.00
Medicine Details
Category | Details |
---|---|
Generic | Ursodeoxycholic acid |
Company | Ibn sina pharmaceuticals ltd |
Also available as |
Title
- Ursodex
Categories
- Medicine
- Pharmaceuticals
- Gastroenterology
Description
- Reduces cholesterol saturation of bile
- Promotes dissolution of gallstones
- Reduces cholesterol absorption
- Suppresses liver cholesterol synthesis
- Improves cholestatic liver diseases
Indications
- Cholestasis (Jaundice)
- Viral Hepatitis
- Alcoholic Fatty Liver
- Primary Billiary Cirrhosis (PBC)
- Primary Sclerosing Cholangitis (PSC)
- Dissolution of Gallstones
- Non-Alcoholic Steato Hepatitis (NASH)
Dosage and Administration
- 8-12 mg/kg/day for dissolution of gallstones
- 10-15 mg/kg/day for primary biliary cirrhosis
- 600 mg/day for acute viral hepatitis
- 300 mg/day for alcoholic fatty liver
- 25-30 mg/kg/day for primary sclerosing cholangitis
Pharmacology
- Decreases secretion of cholesterol in bile
- Reduces cholesterol absorption
- Suppresses liver cholesterol synthesis
- Promotes formation of liquid cholesterol crystal complexes
- Improves cholestatic liver diseases
Interaction
- Avoid concomitant use with oestrogenic hormones
- Avoid concomitant use with bile-acid binding drugs
Contraindications
- Non-functioning gall-bladder
- Calcified and pigmented gallstones
- Inflammatory bowel disease
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Gallstone opacilication
- Pruritus
Pregnancy and Lactation
- Pregnancy category B
- No evidence of harm reported in pregnancy
- Effectively used for cholestasis of pregnancy
- No documented problems regarding breastfeeding
Precautions and Warnings
- Use cautiously in those with liver disease
Therapeutic Class
- Anti-gallstones drugs: Bile Acids
Storage Conditions
- Store below 25°C
- Protected from light and moisture
- Keep out of the reach of children