Ursodex 150 mg (Tablet)

Unit Price: ৳ 12.00 (4 x 10: ৳ 480.00)
Strip Price: ৳ 120.00

Medicine Details

Title

  • Ursodex

Categories

  • Medicine
  • Pharmaceuticals
  • Gastroenterology

Description

  • Reduces cholesterol saturation of bile
  • Promotes dissolution of gallstones
  • Reduces cholesterol absorption
  • Suppresses liver cholesterol synthesis
  • Improves cholestatic liver diseases

Indications

  • Cholestasis (Jaundice)
  • Viral Hepatitis
  • Alcoholic Fatty Liver
  • Primary Billiary Cirrhosis (PBC)
  • Primary Sclerosing Cholangitis (PSC)
  • Dissolution of Gallstones
  • Non-Alcoholic Steato Hepatitis (NASH)

Dosage and Administration

  • 8-12 mg/kg/day for dissolution of gallstones
  • 10-15 mg/kg/day for primary biliary cirrhosis
  • 600 mg/day for acute viral hepatitis
  • 300 mg/day for alcoholic fatty liver
  • 25-30 mg/kg/day for primary sclerosing cholangitis

Pharmacology

  • Decreases secretion of cholesterol in bile
  • Reduces cholesterol absorption
  • Suppresses liver cholesterol synthesis
  • Promotes formation of liquid cholesterol crystal complexes
  • Improves cholestatic liver diseases

Interaction

  • Avoid concomitant use with oestrogenic hormones
  • Avoid concomitant use with bile-acid binding drugs

Contraindications

  • Non-functioning gall-bladder
  • Calcified and pigmented gallstones
  • Inflammatory bowel disease

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Gallstone opacilication
  • Pruritus

Pregnancy and Lactation

  • Pregnancy category B
  • No evidence of harm reported in pregnancy
  • Effectively used for cholestasis of pregnancy
  • No documented problems regarding breastfeeding

Precautions and Warnings

  • Use cautiously in those with liver disease

Therapeutic Class

  • Anti-gallstones drugs: Bile Acids

Storage Conditions

  • Store below 25°C
  • Protected from light and moisture
  • Keep out of the reach of children

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