Cardovan Plus 80 mg+12.5 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Valsartan hydrochlorothiazide
Company Eskayef pharmaceuticals ltd
Also available as
Cardovan plus 160 mg tablet

Title

  • Cardovan Plus

Categories

  • Antihypertensive Medication
  • Combined Antihypertensive Preparations

Description

  • Cardovan Plus is indicated for the treatment of hypertension. It contains Valsartan and Hydrochlorothiazide which act as an angiotensin II receptor blocker and a thiazide diuretic, respectively. The medication helps in dilating blood vessels, reducing blood pressure, and increasing the excretion of sodium and chloride.

Dosage and Administration

  • Recommended dosage for hypertension: Valsartan and Hydrochlorothiazide combination once daily. Maximum allowed dose of Valsartan is 320 mg in combination with hydrochlorothiazide 25 mg. No initial dosage adjustment is necessary for elderly patients. Safety and effectiveness in pediatric patients have not been established.

Interaction

  • Possible interactions with diuretics, agents increasing serum potassium, lithium salts, Warfarin, Digoxin, alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, cholestyramine, and colestipol resins.

Contraindications

  • Contraindicated in patients hypersensitive to any component of this product, and in patients with anuria or hypersensitivity to other sulfonamide-derived drugs.

Side Effects

  • Common side effects include headache, dizziness, fatigue, abdominal pain, cough, diarrhea, and nausea. Other potential side effects may include hyperkalemia, impotency, reduced renal function, allergic reactions, dyspnea, constipation, back pain, muscle cramps, rash, anxiety, insomnia, vertigo, and hypotension.

Pregnancy and Lactation

  • Not to be used in pregnancy, especially in 2nd and 3rd trimester. It is not known whether Valsartan is excreted in human milk. Hydrochlorothiazide is excreted in breast milk.

Precautions and Warnings

  • Exercising caution in patients with impaired hepatic function, impaired renal function, heart failure, or myocardial infarction.

Use in Special Populations

  • Use with caution in patients with renal impairment. Loop diuretics are preferred to thiazides in patients with severe renal impairment. Care should be taken in patients with hepatic impairment.

Overdose Effects

  • Manifestations of overdosage may include hypotension, tachycardia, bradycardia, electrolyte depletion, hypokalemia, hypochloremia, dehydration, and potential cardiac arrhythmias if digitalis has been administered. Management includes placing the patient in supine position, IV infusion of normal saline, and monitoring for hemodialysis if necessary.

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Store between 15-30° C.

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