Arnigen 24 mg+26 mg (Tablet)
Unit Price: ৳ 45.00 (3 x 10: ৳ 1,350.00)
Strip Price: ৳ 450.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sacubitril valsartan |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Reduction of cardiovascular death risk
- Hospitalization prevention for heart failure
- Chronic heart failure management
- Pediatric heart failure treatment
- Combination therapy for heart failure
Pharmacology
- Contains neprilysin inhibitor and angiotensin receptor blocker
- Inhibition of neprilysin and angiotensin II
- Increased levels of natriuretic peptides
- Renal effects in heart failure patients
Dosage & Administration
- Recommended starting dose for adults
- Target maintenance dose
- Adjusted dose for pediatric patients
- Dose titration guidelines
- Weight-based dosing for pediatric patients
Interaction
- Dual blockade contraindication
- Potassium-sparing diuretics interaction
- NSAIDs risk
- Lithium interaction
Contraindications
- Hypersensitivity contraindication
- Angioedema history contraindication
- ACE inhibitor concomitant use contraindication
- Aliskiren concomitant use contraindication
Side Effects
- Angioedema
- Hypotension
- Impaired renal function
- Hyperkalemia
- Cough
- Dizziness
Pregnancy & Lactation
- Pediatric use safety
- Geriatric use pharmacokinetics
- Hepatic impairment recommendation
- Renal impairment dosing
Precautions & Warnings
- Angioedema risk
- Symptomatic hypotension risk
- Serum potassium monitoring
- Renal artery stenosis monitoring
Use in Special Populations
- Pediatric safety and effectiveness
- Geriatric pharmacokinetic differences
- Renal impairment dose adjustment
- Hepatic impairment dose adjustment
Overdose Effects
- Limited data on human overdosage
- Likely hypotension result
- Symptomatic treatment
- Unlikely removal by hemodialysis
Storage Conditions
- Keep in a dry place
- Store below 30°C
- Protect from moisture
- Keep out of the reach of children