Aptin M 50 mg+850 mg (Tablet)

Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)

Strip Price: ৳ 250.00

Medicine Details

Category	Details
Generic	Vildagliptin metformin hydrochloride
Company	Aci limited
Also available as	Aptin m 50 mg tablet

Indications

Adjunct to diet and exercises
Improves glycaemic control
Type 2 diabetes mellitus

Pharmacology

Inhibits Dipeptidyl peptidase-4 (DPP-4)
Increases insulin secretion
Decreases glucagon secretion
Lowers plasma glucose
Improves insulin sensitivity

Dosage & Administration

Initiate at twice daily
Take with or just after food
No clinical experience of triple combination with other antidiabetic agents

Interaction

No clinically relevant pharmacokinetic interaction observed with Metformin Hydrochloride
Low potential for drug interactions
No clinically relevant interactions with other oral antidiabetics

Contraindications

Known hypersensitivity to Vildagliptin or Metformin Hydrochloride
Renal disease or dysfunction
Acute myocardial infarction
Septicaemia
Congestive heart failure
Metabolic acidosis
Discontinue during radiologic studies with iodinated contrast materials

Side Effects

Headache
Tremor
Dizziness
Nausea
Hypoglycaemia

Pregnancy & Lactation

Not recommended during pregnancy
Not known if excreted in human milk

Precautions & Warnings

Risk of lactic acidosis with Metformin accumulation
Monitoring of serum creatinine and liver function tests
Special caution in elderly patients
Discontinue in case of liver dysfunction or jaundice
Discontinue before elective surgery with general anaesthesia

Use in Special Populations

Not recommended for pediatric patients
Regular renal function monitoring in elderly patients
Not recommended in patients with renal or hepatic impairment

Therapeutic Class

Oral hypoglycemic preparations

Storage Conditions

Keep in a dry place away from light and heat
Keep out of the reach of children

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