Reclevus Met 50 mg+500 mg (Tablet)
Unit Price: ৳ 20.50 (3 x 10: ৳ 615.00)
Strip Price: ৳ 205.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Vildagliptin metformin hydrochloride |
| Company | Albion laboratories limited |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycaemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibition of DPP-4 enzyme
- Increase in incretin hormones
- Insulin secretion
- Glucagon secretion
- Glucose production reduction
Dosage & Administration
- Initiation based on current Metformin dose
- Twice daily administration
- Morning and evening dosing
- Switch from separate tablets
- Gastrointestinal symptom reduction
Interaction
- No clinically relevant pharmacokinetic interaction
- Low potential for drug interactions
- Not a cytochrome P (CYP) 450 enzyme substrate
- No interaction with oral antidiabetics
- Impact on Cmax and blood AUC of Metformin
Contraindications
- Hypersensitivity to Vildagliptin or Metformin Hydrochloride
- Renal disease or dysfunction
- Acute myocardial infarction
- Septicaemia
- Congestive heart failure
Side Effects
- Headache
- Tremor
- Dizziness
- Nausea
- Hypoglycemia
Pregnancy & Lactation
- No adequate and well controlled studies in pregnant women
- Potential benefit justifies potential risk to the fetus
- Not known excretion in human milk
Precautions & Warnings
- Lactic acidosis
- Serum creatinine monitoring
- Caution in elderly patients
- Liver Function Tests (LFTs) monitoring
- Discontinuation before elective surgery
Use in Special Populations
- Not recommended for pediatric patients
- Renal function monitoring for elderly patients
- Use only in elderly patients with normal renal function
- Contraindicated in patients with renal failure or dysfunction
- Not recommended in patients with hepatic impairment
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Dry place
- Away from light and heat
- Keep out of the reach of children