Reclevus Met 50 mg+500 mg (Tablet)

Unit Price: ৳ 20.50 (3 x 10: ৳ 615.00)

Strip Price: ৳ 205.00

Medicine Details

Category	Details
Generic	Vildagliptin metformin hydrochloride
Company	Albion laboratories limited
Also available as	Reclevus met 50 mg tablet

Indications

Adjunct to diet and exercise
Improves glycaemic control
Type 2 diabetes mellitus

Pharmacology

Inhibition of DPP-4 enzyme
Increase in incretin hormones
Insulin secretion
Glucagon secretion
Glucose production reduction

Dosage & Administration

Initiation based on current Metformin dose
Twice daily administration
Morning and evening dosing
Switch from separate tablets
Gastrointestinal symptom reduction

Interaction

No clinically relevant pharmacokinetic interaction
Low potential for drug interactions
Not a cytochrome P (CYP) 450 enzyme substrate
No interaction with oral antidiabetics
Impact on Cmax and blood AUC of Metformin

Contraindications

Hypersensitivity to Vildagliptin or Metformin Hydrochloride
Renal disease or dysfunction
Acute myocardial infarction
Septicaemia
Congestive heart failure

Side Effects

Headache
Tremor
Dizziness
Nausea
Hypoglycemia

Pregnancy & Lactation

No adequate and well controlled studies in pregnant women
Potential benefit justifies potential risk to the fetus
Not known excretion in human milk

Precautions & Warnings

Lactic acidosis
Serum creatinine monitoring
Caution in elderly patients
Liver Function Tests (LFTs) monitoring
Discontinuation before elective surgery

Use in Special Populations

Not recommended for pediatric patients
Renal function monitoring for elderly patients
Use only in elderly patients with normal renal function
Contraindicated in patients with renal failure or dysfunction
Not recommended in patients with hepatic impairment

Therapeutic Class

Combination Oral hypoglycemic preparations

Storage Conditions

Dry place
Away from light and heat
Keep out of the reach of children

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