Vildaglip M 50 mg+500 mg (Tablet)

Unit Price: ৳ 15.00 (2 x 10: ৳ 300.00)

Strip Price: ৳ 150.00

Medicine Details

Category	Details
Generic	Vildagliptin metformin hydrochloride
Company	Concord pharmaceuticals ltd
Also available as	Vildaglip m 50 mg tablet

Indications

Adjunct to diet and exercises
Improves glycaemic control
Type 2 diabetes mellitus

Pharmacology

Inhibition of DPP-4 enzyme
Increased insulin secretion
Decreased glucagon secretion
Enhanced insulin/glucagon ratio
Hepatic glucose production reduction
Lowering plasma glucose levels
Improved insulin sensitivity

Dosage & Administration

Twice daily dosage
Morning and evening administration
Switch from separate tablets
Gastrointestinal symptom reduction

Interaction

Low potential for drug interactions
No CYP 450 enzyme interaction
No interaction with other antidiabetic drugs or commonly used medications
Increased Cmax and blood AUC of Metformin with certain medications

Contraindications

Hypersensitivity to Vildagliptin or Metformin
Renal disease or dysfunction
Acute myocardial infarction
Septicaemia
Congestive heart failure
Metabolic acidosis
Radiologic studies involving iodinated contrast materials

Side Effects

Headache
Tremor
Dizziness
Nausea
Hypoglycemia

Pregnancy & Lactation

Not recommended during pregnancy
No adequate studies in pregnant women
Should not be administered to breastfeeding women

Precautions & Warnings

Risk of lactic acidosis
Monitoring serum creatinine levels
Special caution in elderly patients
Liver Function Tests monitoring
Discontinuation before elective surgery with general anesthesia

Use in Special Populations

Not recommended for children below 18 years
Renal function monitoring in elderly patients
Not recommended in patients with renal or hepatic impairment

Therapeutic Class

Combination Oral hypoglycemic preparations

Storage Conditions

Dry place away from light and heat
Keep out of the reach of children

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