Sucovil-M 50 mg+500 mg (Tablet)
Unit Price: ৳ 21.00 (3 x 6: ৳ 378.00)
Strip Price: ৳ 126.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Vildagliptin metformin hydrochloride |
| Company | Globe pharmaceuticals ltd |
Indications
- Adjunct to diet and exercises
- Improves glycaemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibits DPP-4 enzyme
- Increase in insulin secretion
- Decrease in glucagon secretion
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Initiated at twice daily
- 1 tablet in the morning and 1 in the evening
- Recommended dose not exceeding 100 mg of vildagliptin
Interaction
- Low potential for drug interactions
- Does not interact with CYP 450 enzymes
- No clinically relevant interactions with other oral antidiabetics
- Furosemide, nifedipine, and glyburide increase Cmax and blood AUC of Metformin
Contraindications
- Known hypersensitivity
- Renal disease or dysfunction
- Acute myocardial infarction and septicaemia
- Congestive heart failure
- Acute or chronic metabolic acidosis
- Use of iodinated contrast materials
Side Effects
- Headache
- Tremor
- Dizziness
- Nausea
- Hypoglycaemia
Pregnancy & Lactation
- Not recommended during pregnancy
- Unknown excretion in human milk
Precautions & Warnings
- Lactic acidosis can occur
- Serum creatinine monitoring
- Caution in elderly patients
- Liver Function Tests (LFTs) monitoring
- Discontinue 48 hours before elective surgery
Use in Special Populations
- Not recommended for pediatric patients
- Caution in geriatric patients
- Not recommended in renal or hepatic impairment
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children