Sucovil-M 50 mg+500 mg (Tablet)

Unit Price: ৳ 21.00 (3 x 6: ৳ 378.00)
Strip Price: ৳ 126.00

Medicine Details

Category Details
Generic Vildagliptin metformin hydrochloride
Company Globe pharmaceuticals ltd

Indications

  • Adjunct to diet and exercises
  • Improves glycaemic control
  • Type 2 diabetes mellitus

Pharmacology

  • Inhibits DPP-4 enzyme
  • Increase in insulin secretion
  • Decrease in glucagon secretion
  • Lowers basal and postprandial plasma glucose
  • Improves insulin sensitivity

Dosage & Administration

  • Initiated at twice daily
  • 1 tablet in the morning and 1 in the evening
  • Recommended dose not exceeding 100 mg of vildagliptin

Interaction

  • Low potential for drug interactions
  • Does not interact with CYP 450 enzymes
  • No clinically relevant interactions with other oral antidiabetics
  • Furosemide, nifedipine, and glyburide increase Cmax and blood AUC of Metformin

Contraindications

  • Known hypersensitivity
  • Renal disease or dysfunction
  • Acute myocardial infarction and septicaemia
  • Congestive heart failure
  • Acute or chronic metabolic acidosis
  • Use of iodinated contrast materials

Side Effects

  • Headache
  • Tremor
  • Dizziness
  • Nausea
  • Hypoglycaemia

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Unknown excretion in human milk

Precautions & Warnings

  • Lactic acidosis can occur
  • Serum creatinine monitoring
  • Caution in elderly patients
  • Liver Function Tests (LFTs) monitoring
  • Discontinue 48 hours before elective surgery

Use in Special Populations

  • Not recommended for pediatric patients
  • Caution in geriatric patients
  • Not recommended in renal or hepatic impairment

Therapeutic Class

  • Combination Oral hypoglycemic preparations

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Related Brands