Indag-Met 50 mg+500 mg (Tablet)

Unit Price: ৳ 21.00 (2 x 10: ৳ 420.00)
Strip Price: ৳ 210.00

Medicine Details

Indications

  • Adjunct to diet and exercises
  • Improves glycaemic control
  • Type 2 diabetes mellitus

Pharmacology

  • Inhibits Dipeptidyl peptidase-4
  • Increases insulin secretion
  • Decreases glucagon secretion
  • Lowers basal and postprandial plasma glucose
  • Improves insulin sensitivity

Dosage & Administration

  • Twice daily dosing
  • Initiated based on current Metformin dose
  • Switching from separate tablets

Interaction

  • No clinically relevant pharmacokinetic interaction between Vildagliptin and Metformin Hydrochloride
  • Low potential for drug interactions
  • No interactions with other oral antidiabetics observed

Contraindications

  • Hypersensitivity to Vildagliptin or Metformin Hydrochloride
  • Renal disease or dysfunction
  • Acute myocardial infarction
  • Septicaemia
  • Congestive heart failure
  • Metabolic acidosis
  • Radiologic studies involving intravascular administration of iodinated contrast materials

Side Effects

  • Headache
  • Tremor
  • Dizziness
  • Nausea
  • Hypoglycaemia

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Not known if excreted in human milk

Precautions & Warnings

  • Lactic acidosis risk
  • Renal function monitoring
  • Liver function tests monitoring
  • Caution in elderly patients
  • Discontinuation before surgery

Use in Special Populations

  • Not recommended for pediatric patients
  • Renal function monitoring in geriatric patients
  • Not for use in patients with renal failure or dysfunction
  • Not recommended in patients with hepatic impairment

Therapeutic Class

  • Combination Oral hypoglycemic preparations

Storage Conditions

  • Keep in dry place
  • Away from light and heat
  • Keep out of reach of children

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