Indag-Met 50 mg+500 mg (Tablet)
Unit Price: ৳ 21.00 (2 x 10: ৳ 420.00)
Strip Price: ৳ 210.00
Medicine Details
Category | Details |
---|---|
Generic | Vildagliptin metformin hydrochloride |
Company | Pharmasia limited |
Also available as |
Indications
- Adjunct to diet and exercises
- Improves glycaemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibits Dipeptidyl peptidase-4
- Increases insulin secretion
- Decreases glucagon secretion
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Twice daily dosing
- Initiated based on current Metformin dose
- Switching from separate tablets
Interaction
- No clinically relevant pharmacokinetic interaction between Vildagliptin and Metformin Hydrochloride
- Low potential for drug interactions
- No interactions with other oral antidiabetics observed
Contraindications
- Hypersensitivity to Vildagliptin or Metformin Hydrochloride
- Renal disease or dysfunction
- Acute myocardial infarction
- Septicaemia
- Congestive heart failure
- Metabolic acidosis
- Radiologic studies involving intravascular administration of iodinated contrast materials
Side Effects
- Headache
- Tremor
- Dizziness
- Nausea
- Hypoglycaemia
Pregnancy & Lactation
- Not recommended during pregnancy
- Not known if excreted in human milk
Precautions & Warnings
- Lactic acidosis risk
- Renal function monitoring
- Liver function tests monitoring
- Caution in elderly patients
- Discontinuation before surgery
Use in Special Populations
- Not recommended for pediatric patients
- Renal function monitoring in geriatric patients
- Not for use in patients with renal failure or dysfunction
- Not recommended in patients with hepatic impairment
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Keep in dry place
- Away from light and heat
- Keep out of reach of children
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