Indag-Met 50 mg+850 mg (Tablet)
Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00
Medicine Details
Category | Details |
---|---|
Generic | Vildagliptin metformin hydrochloride |
Company | Pharmasia limited |
Also available as |
Indications
- Adjunct to diet and exercises for type 2 diabetes mellitus
- Improves glycaemic control
- For patients not adequately controlled on Metformin Hydrochloride or Vildagliptin alone
- For patients already treated with the combination of Vildagliptin and Metformin Hydrochloride
Pharmacology
- Inhibits DPP-4 enzyme
- Increases insulin secretion
- Decreases glucagon secretion
- Lowers both basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Recommended for adults
- May be initiated at twice daily dosing
- May be taken with or just after food to reduce gastrointestinal symptoms
Interaction
- No clinically relevant pharmacokinetic interaction observed when co-administered with Metformin Hydrochloride
- Low potential for drug interactions with other medications
- Some medications may increase Cmax and blood AUC of Metformin
Contraindications
- Contraindicated in patients with known hypersensitivity to Vildagliptin or Metformin Hydrochloride or to any of the excipients
- Patients with renal disease or dysfunction
- Patients with acute myocardial infarction and septicaemia
Side Effects
- Common side effects include headache, tremor, dizziness, nausea, and hypoglycemia
Pregnancy & Lactation
- Not recommended for use during pregnancy unless the potential benefit justifies the potential risk to the fetus
- Not recommended for breastfeeding women
Precautions & Warnings
- Lactic acidosis can occur due to Metformin accumulation
- Serum creatinine should be monitored regularly
- Liver Function Tests (LFTs) should be monitored prior to initiation and periodically thereafter
- Special caution in elderly patients and those with impaired renal function
Use in Special Populations
- Not recommended for use in pediatric patients below 18 years of age
- Elderly patients should have their renal function monitored regularly
- Not recommended in patients with renal or hepatic impairment
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Related Brands
- Indag-Met 50 mg+500 mg (Tablet) - pharmasia-limited
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- Sucovil-M 50 mg+500 mg (Tablet) - globe-pharmaceuticals-ltd
- Vildaglip M 50 mg+500 mg (Tablet) - concord-pharmaceuticals-ltd