Indag-Met 50 mg+850 mg (Tablet)

Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00

Medicine Details

Category Details
Generic Vildagliptin metformin hydrochloride
Company Pharmasia limited
Also available as
Indag met 50 mg tablet

Indications

  • Adjunct to diet and exercises for type 2 diabetes mellitus
  • Improves glycaemic control
  • For patients not adequately controlled on Metformin Hydrochloride or Vildagliptin alone
  • For patients already treated with the combination of Vildagliptin and Metformin Hydrochloride

Pharmacology

  • Inhibits DPP-4 enzyme
  • Increases insulin secretion
  • Decreases glucagon secretion
  • Lowers both basal and postprandial plasma glucose
  • Improves insulin sensitivity

Dosage & Administration

  • Recommended for adults
  • May be initiated at twice daily dosing
  • May be taken with or just after food to reduce gastrointestinal symptoms

Interaction

  • No clinically relevant pharmacokinetic interaction observed when co-administered with Metformin Hydrochloride
  • Low potential for drug interactions with other medications
  • Some medications may increase Cmax and blood AUC of Metformin

Contraindications

  • Contraindicated in patients with known hypersensitivity to Vildagliptin or Metformin Hydrochloride or to any of the excipients
  • Patients with renal disease or dysfunction
  • Patients with acute myocardial infarction and septicaemia

Side Effects

  • Common side effects include headache, tremor, dizziness, nausea, and hypoglycemia

Pregnancy & Lactation

  • Not recommended for use during pregnancy unless the potential benefit justifies the potential risk to the fetus
  • Not recommended for breastfeeding women

Precautions & Warnings

  • Lactic acidosis can occur due to Metformin accumulation
  • Serum creatinine should be monitored regularly
  • Liver Function Tests (LFTs) should be monitored prior to initiation and periodically thereafter
  • Special caution in elderly patients and those with impaired renal function

Use in Special Populations

  • Not recommended for use in pediatric patients below 18 years of age
  • Elderly patients should have their renal function monitored regularly
  • Not recommended in patients with renal or hepatic impairment

Therapeutic Class

  • Combination Oral hypoglycemic preparations

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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