G-Xylometazoline 0.1% (Nasal Drop)
Medicine Details
| Category | Details |
|---|---|
| Generic | Xylometazoline hydrochloride |
| Company | Gonoshasthaya pharma ltd |
Indications
- Nasal congestion in colds, rhinitis, sinusitis, headache
- Tubal block and serous otitis media associated with nasal congestion
Description
G-Xylometazoline is a sympathomimetic agent with marked alpha-adrenergic activity and is intended for use in the nose. It constricts the nasal blood vessels, thereby decongesting the mucosa of the nose and neighboring regions of the pharynx. This enables patients suffering from colds to breathe more easily through the nose. The effect of G-Xylometazoline begins within a few minutes and persists for several hours.
Pharmacology
Nasal congestion is caused by various etiologies, such as rhinosinusitis and allergic or non-allergic rhinitis, leading to congestion of the venous sinusoids lining the nasal mucosa. Activation of alpha-adrenergic receptors leads to vasoconstriction of the blood vessels of the nasal mucosa and resumption of nasal airflow.
Dosage & Administration
- Adults: 0.1%: 2 or 3 drops in each nostril two to three times daily. 0.1% should not be used for children under the age of 12 years
- Children 6 to 12 years of age: 0.05%: 2 or 3 drops in each nostril two or three times daily
- Children less than 6 years of age: 0.05%: 1 drop in each nostril two or three times daily
- Infants less than 3 months: Not to be used in infants less than 3 months
- Children from 2-12 years old: 0.05%: 1 spray, per nostril not more often than three times per day
- Adults and adolescents (over 12 years of age): 0.1%: 1 spray into each nostril, 1 to 3 times daily as needed. Do not exceed 3 applications daily into each nostril. Or, as directed by the registered physician
Interaction
No drug interactions have been reported.
Contraindications
Xylometazoline nasal drops is contraindicated in patients with transsphenoidal hypophysectomy or surgery exposing the dura mater. It is also contraindicated in patients who are hypersensitive to Xylometazoline. Each Xylometazoline nasal drop should be used by one person only to prevent any cross-infection. Patients are advised not to take decongestants for more than seven consecutive days.
Side Effects
- A burning sensation in the nose and throat
- Local irritation
- Nausea and dryness of the nasal mucosa.
Pregnancy & Lactation
Pregnancy category C. Xylometazoline should not be used during pregnancy. The use of Otrivin while breastfeeding should only take place on the instructions of a doctor.
Precautions & Warnings
G-G-Xylometazoline nasal drops for adults (0.1%) should not be used for children below 12 years. Drops should not be used for a long time in cases with chronic rhinitis. Prolonged use of the drops may cause rebound congestion and drug-induced rhinitis.
Therapeutic Class
Nasal Anti-histamine preparations
Storage Conditions
Protect from light. For reasons of hygiene, do not use the bottle more than 28 days after opening it.