AH 200 mg/5 ml (Oral Suspension)

10 ml bottle: ৳ 20.10

Medicine Details

Category Details
Generic Albendazole
Company Drug international ltd
Also available as
Ah 400 mg chewable tablet

Indications

  • Indicated in single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid

Description

  • Benzimidazole anthelmintic
  • Active against most nematodes and some cestodes
  • Used in the treatment of intestinal nematode infections and in higher doses in the treatment of hydatid disease
  • Vermicidal, ovicidal, and larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Exhibits vermicidal, ovicidal and larvicidal activities
  • Blocks glucose uptake in susceptible helminths
  • Depletes energy level leading to immobilization of the parasite
  • Extensively metabolized, probably in the liver
  • Poorly absorbed from the gastrointestinal tract but undergoes extensive first-pass metabolism

Dosage & Administration

  • Adults & children over 2 years: 400 mg as a single dose for various infections
  • Children of 1-2 years: Recommended dose of 200 mg
  • Children under 1 year: Not recommended
  • In Hydatid disease (Echinococcosis): Dosage varies based on body weight for different treatment cycles
  • In giardiasis: 400 mg once daily for five days

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not normally used in neonates
  • Reduced dose may be indicated in children weighing less than 10 kg
  • Not recommended in pregnant women or women thought to be pregnant
  • No evidence to suggest alteration of dose in renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia
  • Rash
  • Fever
  • Blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsion and meningism in cerebral disease

Pregnancy & Lactation

  • Albendazole is FDA Pregnancy category C
  • Avoided in pregnancy and lactation unless potential benefits outweigh possible risks to the fetus

Precautions & Warnings

  • Blood counts and liver function tests before treatment and twice during each cycle
  • Breastfeeding
  • Exclude pregnancy before starting treatment
  • Constant medical supervision and regular monitoring in the treatment of Echinococcosis

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of the reach of children

Related Brands