Orben 400 mg (Chewable Tablet)
Unit Price: ৳ 3.76
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Orbit pharmaceuticals ltd |
Indications
- Hookworm infestations
- Roundworm infestations
- Threadworm infestations
- Whipworm infestations
- Strongyloides infestations
- Tapeworm infestations
- Opisthorchi infestations
- Hydatid infestations
Description
- Benzimidazole anthelmintic
- Active against most nematodes
- Active against some cestodes
- Vermicidal activity
- Ovicidal activity
- Larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Blocks glucose uptake in helminths
- Depletes energy level in helminths
- Immobilization of parasites
- Metabolized in the liver
- Poorly absorbed from gastrointestinal tract
- Plasma half-life of about 8.5 hrs
Dosage & Administration
- Recommended dose for adults & children over 2 years
- Recommended dose for children of 1-2 years
- Not recommended for children under 1 year
- Dosing for hydatid disease (Echinococcosis)
- Dosing for strongyloidiasis or taeniasis
- Dosing for giardiasis
Interaction
- No reported pharmacodynamic interaction
- No reported pharmacokinetic interaction
Contraindications
- Not normally used in neonates
- Possible reduction in dose for children under 10 kg
- Should not be used in pregnant women
- No evidence to alter dose in concurrent disease
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia
- Rash
- Fever
- Blood disorders
- Allergic shock
- Convulsion
- Meningism
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoided in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Blood counts and liver function tests prior to treatment
- Breastfeeding precaution
- Exclude pregnancy before treatment
- Constant medical supervision for Echinococcosis treatment
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in dry place
- Away from light and heat
- Keep out of reach of children