Orben 400 mg (Chewable Tablet)

Unit Price: ৳ 3.76

Medicine Details

Category	Details
Generic	Albendazole
Company	Orbit pharmaceuticals ltd

Indications

Hookworm infestations
Roundworm infestations
Threadworm infestations
Whipworm infestations
Strongyloides infestations
Tapeworm infestations
Opisthorchi infestations
Hydatid infestations

Description

Benzimidazole anthelmintic
Active against most nematodes
Active against some cestodes
Vermicidal activity
Ovicidal activity
Larvicidal activity
Inhibitory effect on tubulin polymerization

Pharmacology

Broad spectrum anthelmintic
Blocks glucose uptake in helminths
Depletes energy level in helminths
Immobilization of parasites
Metabolized in the liver
Poorly absorbed from gastrointestinal tract
Plasma half-life of about 8.5 hrs

Dosage & Administration

Recommended dose for adults & children over 2 years
Recommended dose for children of 1-2 years
Not recommended for children under 1 year
Dosing for hydatid disease (Echinococcosis)
Dosing for strongyloidiasis or taeniasis
Dosing for giardiasis

Interaction

No reported pharmacodynamic interaction
No reported pharmacokinetic interaction

Contraindications

Not normally used in neonates
Possible reduction in dose for children under 10 kg
Should not be used in pregnant women
No evidence to alter dose in concurrent disease

Side Effects

Gastrointestinal disturbances
Headache
Dizziness
Changes in liver enzymes
Reversible alopecia
Rash
Fever
Blood disorders
Allergic shock
Convulsion
Meningism

Pregnancy & Lactation

FDA Pregnancy category C
Avoided in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

Blood counts and liver function tests prior to treatment
Breastfeeding precaution
Exclude pregnancy before treatment
Constant medical supervision for Echinococcosis treatment

Therapeutic Class

Anthelmintic

Storage Conditions

Keep in dry place
Away from light and heat
Keep out of reach of children

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