AB-DS 400 mg (Chewable Tablet)

Unit Price: ৳ 3.00

Medicine Details

Category Details
Generic Albendazole
Company Prime pharmaceuticals ltd

Indications

  • Single infestation
  • Mixed infestation
  • Hookworm
  • Roundworm
  • Threadworm
  • Whipworm
  • Strongyloides
  • Tapeworm
  • Opisthorchi
  • Hydatid

Description

  • Benzimidazole anthelmintic
  • Active against nematodes
  • Active against cestodes
  • Vermicidal activity
  • Ovicidal activity
  • Larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Blocks glucose uptake in helminths
  • Depletes energy level of helminths
  • Immobility of parasites
  • Metabolized in the liver
  • Poorly absorbed from gastrointestinal tract
  • Excreted in urine

Dosage & Administration

  • Recommended dose for adults
  • Recommended dose for children over 2 years
  • Recommended dose for children of 1-2 years
  • Not recommended for children under 1 year
  • Recommended dose for hydatid disease
  • Recommended dose for strongyloidiasis
  • Recommended dose for taeniasis
  • Recommended dose for giardiasis

Interaction

  • No reported pharmacodynamic interaction
  • No reported pharmacokinetic interaction

Contraindications

  • Not normally used in neonates
  • Dose reduction for children weighing less than 10 kg
  • Avoid in pregnant women
  • No evidence for dose alteration in renal, hepatic or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia
  • Rash
  • Fever
  • Blood disorders
  • Allergic shock if cyst leakage
  • Convulsions
  • Meningism in cerebral disease

Pregnancy & Lactation

  • US FDA Pregnancy category C
  • Avoid in pregnancy and lactation
  • Potential benefits vs. possible risks

Precautions & Warnings

  • Blood counts and liver function tests before treatment
  • Twice during each cycle
  • Breastfeeding precautions
  • Exclude pregnancy before treatment
  • Medical supervision for Echinococcosis treatment
  • Regular monitoring of serum-transaminase

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in dry place
  • Away from light and heat
  • Keep out of reach of children

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