Vastor 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Ad din pharmaceuticals ltd |
Title
Vastor 10 mg Tablet
Categories
- Cholesterol-lowering Medication
- Cardiovascular Medication
Description
Vastor 10 mg Tablet is a selective inhibitor of HMG-CoA reductase, indicated as an adjunct to diet to reduce cholesterol and triglycerides levels in various conditions such as heterozygous and homozygous familial hypercholesterolaemia, mixed dyslipidemia, hypertriglyceridaemia, dysbetalipoproteinaemia, asymptomatic or mild to moderate symptomatic coronary artery disease, hypercholesterolemia associated with or exacerbated by diabetes mellitus or renal transplantation.
Strength
10 mg
Packaging
Blister pack
Dosage form
Tablet
Manufacturer
Manufacturer Name
Color
White
Shape
Oval
Size
11mm x 5mm x 3mm
Weight
300 mg
Active ingredient
Atorvastatin
Inactive ingredients
- Lactose Monohydrate
- Microcrystalline Cellulose
- Croscarmellose Sodium
- Povidone
- Magnesium Stearate
- Opadry II White
Absorption
Rapidly absorbed after oral administration with maximum plasma concentrations within 1 to 2 hours.
Bioavailability
Approximately 14%
Metabolism
Extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products.
Excretion
Primarily in bile following hepatic and/or extra-hepatic metabolism with mean plasma elimination half-life of approximately 14 hours.
Interactions
- Cyclosporine
- Fibric Acid Derivatives
- Niacin
- Erythromycin
- Azole Antifungals
- Antacid
- Colestipol
- Digoxin
- Erythromycin
- Oral Contraceptives
- Warfarin
Contraindications
- Hypersensitivity to any component of the medication
- Active liver disease
- Unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
Side effects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
Pregnancy contraindications
- Atorvastatin is contraindicated during pregnancy
- Not recommended during lactation due to potential serious adverse reactions
Precautions warnings
- Liver function tests should be performed before initiation of treatment and periodically thereafter
- Used with caution in patients who consume substantial quantities of alcohol or have a history of liver disease
- Therapy should be discontinued if markedly elevated CPK levels occur or myopathy is diagnosed or suspected.
Special populations
- Geriatric: Plasma concentrations are higher in healthy elderly subjects
- Pediatric: Pharmacokinetic data not available
- Gender: No clinically significant difference in LDL-C reduction between men and women
- Renal insufficiency: No influence on plasma concentrations or LDL-C reduction
- Hemodialysis: Not expected to significantly enhance clearance since the drug is extensively bound to plasma proteins
- Hepatic insufficiency: Plasma concentrations are markedly increased in patients with chronic alcoholic liver disease
Overdose effects
Specific treatment is not available for atorvastatin overdose. The patient should be treated symptomatically and supportive measures instituted.
Therapeutic class
Other Anti-anginal & Anti-ischaemic drugs, Statins
Storage conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical structure
- Molecular formula: C33H35FN2O5
- Image url: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg
Common questions
- What is Vastor 10 mg Tablet?: It is a selective inhibitor of HMG-CoA reductase used to avoid heart attacks and treat conditions such as Mixed Dyslipidemia and Hypertriglyceridemia.
- How should I take Vastor 10 mg Tablet?: It should be taken by mouth once daily, at the same time each day, with or without food.
- What are the uses of Vastor 10 mg Tablet?: It is used for the treatment of diseases like Mixed Dyslipidemia and Hypertriglyceridemia and conditions like heart attacks and Primary Hypercholesterolemia.
- What are the Side Effects of Vastor 10 mg Tablet?: Possible side-effects include cough, muscle pain, breathing difficulty, and running nose.
- What are the instructions for storage and disposal Vastor 10 mg Tablet?: Store at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.
- Is Vastor 10 mg Tablet used for lowering cholesterol?: Yes, it is used to lower cholesterol and triglycerides present in the blood.
- Will taking Vastor 10 mg Tablet increase my risk of diabetes?: It can slightly affect blood sugar levels, requiring regular monitoring during treatment.
- For how long do I need to take Vastor 10 mg Tablet? Is it safe for long-term use?: It should be taken for the prescribed duration. Long-term use is safe when taken as directed by the doctor.
- Does Vastor 10 mg Tablet cause weight loss?: No studies report that it causes weight loss.
- Can I stop taking Vastor 10 mg Tablet?: Do not stop without informing your doctor to avoid worsening your condition.
- Does Vastor 10 mg Tablet cause memory loss?: Memory loss is a very rare side effect.
- Does Vastor 10 mg Tablet make you tired?: It can make you feel tired, but the exact reason behind this is still unknown.
- Can Vastor 10 mg Tablet be prescribed to children?: It should be used by adults and caution must be exercised in children above 10 years old.