Onvas 10 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | One pharma ltd |
| Also available as |
Title
- Onvas 10 mg Tablet
Categories
- Medicine
- Pharmaceutical
Indications
- Reduction of total cholesterol
- Reduction of LDL cholesterol
- Reducing triglycerides levels
- Treatment of heterozygous familial hypercholesterolaemia
- Treatment of homozygous familial hypercholesterolaemia
- Treatment of mixed dyslipidemia
- Treatment of hypertriglyceridaemia
- Treatment of dysbetalipoproteinaemia
- Reduction of cardiac ischaemic events
- Treatment of hypercholesterolemia associated with diabetes mellitus
- Treatment of hypercholesterolemia associated with renal transplantation
Pharmacology
- Selective inhibitor of HMG-CoA reductase
- Lowering plasma cholesterol and lipoprotein levels
- Inhibiting cholesterol synthesis
- Increasing hepatic LDL receptors
- Rapid absorption after oral administration
- Extensive metabolism by cytochrome P450 3A4
- Elimination primarily in bile
- Plasma elimination half-life of approximately 14 hours
Dosage & Administration
- Adults dosage of 10-80 mg once daily
- Child (10-18 years) dosage of 10-20 mg once daily
- Starting dose of 10 or 20 mg once daily
- Dosage range of 10 to 80 mg once daily
- Lipid level analysis within 2 to 4 weeks of initiation
Interaction
- Increased risk of myopathy with concurrent administration of certain drugs
- Altered plasma concentrations when coadministered with antacid, colestipol, digoxin, erythromycin, oral contraceptives
- No clinically significant effect on prothrombin time when administered with warfarin
Contraindications
- Hypersensitivity to any component
- Active liver disease or unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
Side Effects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
Pregnancy & Lactation
- Contraindicated during pregnancy
- Rare reports of congenital anomalies
- Not recommended during breastfeeding
Precautions & Warnings
- Liver function tests before initiation of treatment
- Discontinuation if markedly elevated CPK levels occur or myopathy is diagnosed or suspected
Use in Special Populations
- Higher plasma concentrations in elderly subjects
- No clinically significant difference in LDL-C reduction between men and women
- No influence on plasma concentrations or LDL-C reduction in renal disease
Overdose Effects
- Specific treatment not available
- Symptomatic treatment
- Liver function tests and serum CK levels monitoring
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C33H35FN2O5
Common Questions
- What is Onvas 10 mg Tablet?
- How should I take Onvas 10 mg Tablet?
- What are the uses of Onvas 10 mg Tablet?
- Side Effects of Onvas 10 mg Tablet
- Instructions for storage and disposal of Onvas 10 mg Tablet
- Is it used for lowering cholesterol?
- Will taking it increase the risk of diabetes?
- For how long should it be taken?
- Does it cause weight loss?
- Can it be prescribed to children?
- Is it a blood thinner?
Quick Tips
- Safe when taken with food
- Monitor fatigue, muscle weakness, and liver function
- Inform doctor about kidney disease, liver disease, or diabetes
- Avoid use during pregnancy or breastfeeding