Labeta 100 mg (Tablet)
Unit Price: ৳ 6.02 (6 x 10: ৳ 361.20)
Strip Price: ৳ 60.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Labetalol hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
- Hypertension in pregnancy
- Hypertensive crisis
- Anaesthesia for hypotensive technique
Pharmacology
- Adrenergic receptor-blocking agent
- Alpha 1-adrenergic and nonselective beta-adrenergic receptor-blocking actions
- Decrease in blood pressure
- Plasma half-life of 6 to 8 hours
- Renal function in hypertensive patients
Dosage & Administration
- Oral dosage for adults and elderly patients
- Severe hypertension dosage
- Intravenous injection and infusion dosages for various conditions
- Titration increments
- Intravenous infusion fluid compatibility
Interaction
- Enhancement of hypotensive effects of halothane
- Concomitant use with antiarrhythmic agents or calcium antagonists
- Reduction of hypotensive effect with prostaglandin synthetase inhibitors
- Increased incidence of tremor with tricyclic antidepressants
- Bioavailability increase with cimetidine
Contraindications
- Hypersensitivity to the medicine
- Second or third degree heart block
- Uncontrolled heart failure
- Bronchial asthma or obstructive lung disorders
Side Effects
- Postural hypotension
- Tiredness
- Weakness
- Headache
- Rashes
- Scalp tingling
- Difficulty in micturition
- Epigastric pain
- Nausea
- Vomiting
- Liver damage
Pregnancy & Lactation
- No reproducible evidence of fetal malformations in teratogenic studies
- No apparent effect on labor and delivery in pregnant women with hypertension
- Excretion in human milk
- Caution in nursing women
Precautions & Warnings
- Rare reports of severe hepatocellular injury
- Reversible hepatic injury
- Caution in patients with hepatic impairment
- Caution in patients with peripheral vascular disease
Overdose Effects
- Excessive hypotension
- Excessive bradycardia
- Gastric lavage
- Pharmacologically induced emesis
- Atropine administration for excessive bradycardia
- Digitalis glycoside administration for cardiac failure
- Vasopressors administration for hypotension
- Epinephrine administration for bronchospasm
Therapeutic Class
- Alpha adrenoceptor blocking drugs
- Beta-adrenoceptor blocking drugs
Storage Conditions
- Cool and dry place
- Protected from light
- Keep out of reach of children